Die folgenden Gennamen und Gensymbole werden für Antigen Jun Proto-Oncogene über verschiedene Spezies hinweg verwendet:

jun oncogene (JUN), Jun oncogene (Jun), v-jun sarcoma virus 17 oncogene homolog (avian) (jun), jun oncogene (jun), jun proto-oncogene (JUN)

Zu den weiteren Synonymen zählen:

AP1, AP-1, c-Jun, fj36h07, zgc:65863, wu:fj36h07, jun

Auf Proteinebene tauchen folgende Bezeichner für Antigen Jun Proto-Oncogene auf:

jun oncogene – activator protein 1 – enhancer-binding protein AP1 – Jun activation domain binding protein – v-jun sarcoma virus 17 oncogene homolog – v-jun avian sarcoma virus 17 oncogene homolog – transcription factor AP-1 – AP1 – proto-oncogene c-jun – V-jun avian sarcoma virus 17 oncogene homolog – Avian sarcoma virus 17 (v-jun) oncogene homolog – c-Jun protein – v-jun sarcoma virus 17 oncogene

Jun Proto-Oncogene erfüllt eine Reihe von Funktionen:

R-SMAD binding – RNA polymerase II transcription factor activity – Rho GTPase activator activity – promoter binding – protein dimerization activity – transcription factor activity – transcription factor binding – DNA binding – RNA polymerase II transcription factor activity, enhancer binding – double-stranded DNA binding – protein binding – protein heterodimerization activity – protein homodimerization activity – sequence-specific DNA binding – sequence-specific DNA binding transcription factor activity – transcription activator activity – transcription coactivator activity – transcription repressor activity – beta-catenin binding

Jun Proto-Oncogene spielt in den folgenden Prozessen eine Rolle:

SMAD protein nuclear translocation – SMAD protein signal transduction – cellular process – leading edge cell differentiation – negative regulation of cell proliferation – negative regulation of protein amino acid autophosphorylation – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – regulation of cell cycle – regulation of transcription, DNA-dependent – response to drug – transforming growth factor beta receptor signaling pathway – aging – angiogenesis – cellular response to potassium ion starvation – circadian rhythm – learning – membrane depolarization – negative regulation of DNA binding – positive regulation by host of viral transcription – positive regulation of DNA replication – positive regulation of apoptosis – positive regulation of cell proliferation – positive regulation of monocyte differentiation – positive regulation of neuron apoptosis – positive regulation of smooth muscle cell proliferation – release of cytochrome c from mitochondria – response to cAMP – response to cytokine stimulus – response to hydrogen peroxide – response to lipopolysaccharide – response to mechanical stimulus – response to organic cyclic substance – response to organic substance – transcription from RNA polymerase II promoter – Wnt receptor signaling pathway through beta-catenin – response to cadmium ion – response to methylmercury

Jun Proto-Oncogene ist wie folgt lokalisiert:

cytosol – nuclear chromosome – nucleus – transcription factor complex – nuclear chromatin – nucleoplasm

Quelle: NCBI Entrez Gene, Gene Ontology