Die folgenden Gennamen und Gensymbole werden für Antigen Jumonji, AT Rich Interactive Domain 2 über verschiedene Spezies hinweg verwendet:

jumonji, AT rich interactive domain 2 (JARID2), jumonji, AT rich interactive domain 2 (Jarid2), jumonji, AT rich interactive domain 2a (jarid2a), jumonji, AT rich interactive domain 2 (jarid2), jumonji, AT rich interactive domain 2 (LOC100230783)

Zu den weiteren Synonymen zählen:

JMJ, Jmj, C79929, C79931, jumonji, AI317256, AU045941, JARID2, jarid2, jmj

Auf Proteinebene tauchen folgende Bezeichner für Antigen Jumonji, AT Rich Interactive Domain 2 auf:

jumonji, AT rich interactive domain 2 protein – jumonji homolog – jumonji-like protein – protein Jumonji – jumonji/ARID domain-containing protein 2 – jumonji, AT rich interactive domain 2 – jumonji, AT rich interactive domain 2a – protein Jumonji-like

Jumonji, AT Rich Interactive Domain 2 erfüllt eine Reihe von Funktionen:

DNA binding – protein binding – transcription repressor activity – chromatin binding – histone demethylase activity

Jumonji, AT Rich Interactive Domain 2 spielt in den folgenden Prozessen eine Rolle:

central nervous system development – liver development – multicellular organismal development – negative regulation of cell proliferation – negative regulation of transcription from RNA polymerase II promoter – regulation of transcription – spleen development – thymus development – cell differentiation – chromatin modification – negative regulation of histone methylation – negative regulation of transcription, DNA-dependent – positive regulation of histone H3-K9 methylation – regulation of cell proliferation – stem cell differentiation – transcription

Jumonji, AT Rich Interactive Domain 2 ist wie folgt lokalisiert:

intracellular – nucleus – ESC/E(Z) complex – histone methyltransferase complex

Quelle: NCBI Entrez Gene, Gene Ontology