Die folgenden Gennamen und Gensymbole werden für Antigen Interleukin-6 Receptor über verschiedene Spezies hinweg verwendet:

interleukin 6 receptor (IL6R), interleukin 6 receptor (il6r)

Zu den weiteren Synonymen zählen:

CD126, IL6RA, IL-6R-1, MGC104991, IL-6R-alpha, IL6R, IL-6Ralpha, il-6ra

Auf Proteinebene tauchen folgende Bezeichner für Antigen Interleukin-6 Receptor auf:

interleukin 6 receptor – CD126 antigen – interleukin 6 receptor alpha subunit – IL-6 receptor alpha chain – interleukin 6 receptor alpha

Interleukin-6 Receptor erfüllt eine Reihe von Funktionen:

ciliary neurotrophic factor binding – ciliary neurotrophic factor receptor activity – enzyme binding – interleukin-6 receptor activity – protein homodimerization activity – receptor activity – receptor binding – cytokine receptor activity

Interleukin-6 Receptor spielt in den folgenden Prozessen eine Rolle:

acute-phase response – ciliary neurotrophic factor-mediated signaling pathway – defense response to Gram-negative bacterium – endocrine pancreas development – hepatic immune response – interleukin-6-mediated signaling pathway – monocyte chemotaxis – positive regulation of anti-apoptosis – positive regulation of chemokine production – positive regulation of interleukin-6 production – positive regulation of leukocyte chemotaxis – positive regulation of osteoblast differentiation – positive regulation of peptidyl-tyrosine phosphorylation – positive regulation of smooth muscle cell proliferation – positive regulation of tyrosine phosphorylation of Stat3 protein – regulation of apoptosis – response to cytokine stimulus

Interleukin-6 Receptor ist wie folgt lokalisiert:

apical plasma membrane – extracellular region – integral to membrane – interleukin-6 receptor complex – plasma membrane – membrane

Quelle: NCBI Entrez Gene, Gene Ontology