Die folgenden Gennamen und Gensymbole werden für Antigen Interleukin 4 über verschiedene Spezies hinweg verwendet:

interleukin 4 (IL4), interleukin 4 (Il4)

Zu den weiteren Synonymen zählen:

BSF1, IL-4, BCGF1, BCGF-1, MGC79402, Il-4, IL4, Il4e12, IL-2, BSF-1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Interleukin 4 auf:

interleukin 4 – B cell growth factor 1 – B_cell stimulatory factor 1 – lymphocyte stimulatory factor 1 – interleukin-4 – BSF-1 – OTTMUSP00000005817 – IGG1 induction factor – B-cell growth factor 1 – B-cell stimulatory factor 1 – B-cell IgG differentiation factor – IL-4 – B-cell IGG differentiation factor – Interleukin-4 – Lymphocyte stimulatory factor 1

Interleukin 4 erfüllt eine Reihe von Funktionen:

cytokine activity – growth factor activity – interleukin-4 receptor binding – protein binding – cytokine receptor binding

Interleukin 4 spielt in den folgenden Prozessen eine Rolle:

B cell differentiation – T-helper 2 type immune response – cellular defense response – chemotaxis – cholesterol metabolic process – connective tissue growth factor biosynthetic process – negative regulation of apoptosis – negative regulation of osteoclast differentiation – positive regulation of B cell proliferation – positive regulation of MHC class II biosynthetic process – positive regulation of T cell proliferation – positive regulation of isotype switching to IgE isotypes – positive regulation of isotype switching to IgG isotypes – positive regulation of transcription from RNA polymerase II promoter – regulation of immune response – regulation of isotype switching – regulation of phosphorylation – B cell activation – immune response – negative regulation of acute inflammatory response – negative regulation of chronic inflammatory response – negative regulation of nitric oxide biosynthetic process – positive regulation of B cell activation – positive regulation of activated T cell proliferation – positive regulation of cell proliferation – positive regulation of gene-specific transcription – positive regulation of interleukin-10 production – positive regulation of peptidyl-tyrosine phosphorylation – positive regulation of transcription factor activity – positive regulation of tyrosine phosphorylation of Stat5 protein – regulation of inflammatory response – regulation of proton transport – cellular response to mercury ion – female pregnancy – inflammatory response – response to cytokine stimulus – response to drug – response to ethanol – response to nutrient – response to organic cyclic substance – response to cold

Interleukin 4 ist wie folgt lokalisiert:

extracellular region – extracellular space

Quelle: NCBI Entrez Gene, Gene Ontology