Die folgenden Gennamen und Gensymbole werden für Antigen Interleukin 3 über verschiedene Spezies hinweg verwendet:

interleukin 3 (colony-stimulating factor, multiple) (IL3), interleukin 3 (Il3), interleukin 3 (IL3)

Zu den weiteren Synonymen zählen:

IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF, BPA, PSF, HCGF, Il-3, Csfmu, IL3

Auf Proteinebene tauchen folgende Bezeichner für Antigen Interleukin 3 auf:

interleukin 3 – mast-cell growth factor – P-cell stimulating factor – hematopoietic growth factor – multilineage-colony-stimulating factor – interleukin-3 – OTTMUSP00000005831 – mast cell growth factor – P-cell-stimulating factor – multipotential colony-stimulating factor – colony-stimulating factor, multiple

Interleukin 3 erfüllt eine Reihe von Funktionen:

cytokine activity – growth factor activity – interleukin-3 receptor binding – protein binding

Interleukin 3 spielt in den folgenden Prozessen eine Rolle:

cell-cell signaling – immune response – nervous system development – positive regulation of DNA replication – positive regulation of cell proliferation – positive regulation of peptidyl-tyrosine phosphorylation – positive regulation of survival gene product expression – positive regulation of tyrosine phosphorylation of Stat5 protein – cytokine-mediated signaling pathway – hemopoiesis – myeloid cell apoptosis – negative regulation of apoptosis – negative regulation of autophagy – negative regulation of mast cell apoptosis – positive regulation of JNK cascade – positive regulation of mast cell proliferation – positive regulation of myeloid leukocyte differentiation – positive regulation of protein amino acid phosphorylation – regulation of cell growth – regulation of gene expression – response to hormone stimulus

Interleukin 3 ist wie folgt lokalisiert:

extracellular region – extracellular space – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology