Die folgenden Gennamen und Gensymbole werden für Antigen Interleukin 1, beta über verschiedene Spezies hinweg verwendet:

interleukin 1, beta (IL1B), interleukin 1, beta (il1b)

Zu den weiteren Synonymen zählen:

IL-1, IL1F2, IL1-BETA, IL1B, IL-1BETA, MGC111873, zgc:111873, IL-1B

Auf Proteinebene tauchen folgende Bezeichner für Antigen Interleukin 1, beta auf:

interleukin 1, beta – catabolin – preinterleukin 1 beta – pro-interleukin-1-beta – interleukin-1 beta – IL-1 beta – prointerleukin-1 beta – interleukin-1 beta proprotein – interleukin-beta

Interleukin 1, beta erfüllt eine Reihe von Funktionen:

cytokine activity – growth factor activity – interleukin-1 receptor binding – protein domain specific binding – inorganic diphosphatase activity – magnesium ion binding

Interleukin 1, beta spielt in den folgenden Prozessen eine Rolle:

activation of MAPK activity – anti-apoptosis – apoptosis – cell-cell signaling – cytokine-mediated signaling pathway – elevation of cytosolic calcium ion concentration – embryo implantation – fever – immune response – inflammatory response – leukocyte migration – negative regulation of MAP kinase activity – negative regulation of adiponectin secretion – negative regulation of cell proliferation – negative regulation of glucose transport – negative regulation of insulin receptor signaling pathway – negative regulation of lipid catabolic process – neutrophil chemotaxis – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of JNK cascade – positive regulation of NF-kappaB transcription factor activity – positive regulation of T cell mediated immunity – positive regulation of T cell proliferation – positive regulation of angiogenesis – positive regulation of calcidiol 1-monooxygenase activity – positive regulation of cell adhesion molecule production – positive regulation of cell division – positive regulation of chemokine biosynthetic process – positive regulation of heterotypic cell-cell adhesion – positive regulation of interleukin-2 biosynthetic process – positive regulation of interleukin-6 biosynthetic process – positive regulation of interleukin-6 production – positive regulation of lipid catabolic process – positive regulation of membrane protein ectodomain proteolysis – positive regulation of mitosis – positive regulation of nitric oxide biosynthetic process – positive regulation of protein amino acid phosphorylation – positive regulation of protein export from nucleus – positive regulation vascular endothelial growth factor production – regulation of insulin secretion – response to ATP – response to chemical stimulus – response to lipopolysaccharide – sequestering of triglyceride – signal transduction – smooth muscle adaptation – positive regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of lipid metabolic process – defense response to bacterium – phosphate metabolic process – response to arsenic – response to bacterium

Interleukin 1, beta ist wie folgt lokalisiert:

extracellular region – extracellular space – secretory granule – vesicle – stored secretory granule – cytoplasm

Quelle: NCBI Entrez Gene, Gene Ontology