Die folgenden Gennamen und Gensymbole werden für Antigen Integrin beta 1 über verschiedene Spezies hinweg verwendet:

integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), integrin beta 1 (fibronectin receptor beta) (Itgb1), integrin beta 1 (ITGB1)

Zu den weiteren Synonymen zählen:

CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, Fnrb, gpIIa, AA409975, AA960159, 4633401G24Rik, ITGB1, MGC137337, itgb1-B

Auf Proteinebene tauchen folgende Bezeichner für Antigen Integrin beta 1 auf:

integrin beta 1 – integrin VLA-4 beta subunit – fibronectin receptor beta subunit – integrin, beta 1 subunit (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) – Integrin beta-1-B – integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) – Integrin beta-1 – Integrin subunit beta-1 – Integrin VLA-4 subunit beta – Fibronectin receptor subunit beta

Integrin beta 1 erfüllt eine Reihe von Funktionen:

identical protein binding – integrin binding – protein heterodimerization activity – receptor activity – binding – protein binding – peptide binding – protein kinase binding

Integrin beta 1 spielt in den folgenden Prozessen eine Rolle:

B cell differentiation – G1/S transition of mitotic cell cycle – cardiac muscle cell differentiation – cell adhesion – cell fate specification – cell-cell adhesion mediated by integrin – cell-matrix adhesion – cellular defense response – germ cell migration – homophilic cell adhesion – in utero embryonic development – integrin-mediated signaling pathway – interspecies interaction between organisms – leukocyte adhesion – negative regulation of cell differentiation – positive regulation of cell proliferation – regulation of cell cycle – sarcomere organization – cellular calcium ion homeostasis – neuron projection morphogenesis – positive regulation of MAPKKK cascade – regulation of G-protein coupled receptor protein signaling pathway – tissue homeostasis

Integrin beta 1 ist wie folgt lokalisiert:

cell surface – focal adhesion – integral to membrane – integrin complex – melanosome – neuromuscular junction – ruffle membrane – sarcolemma – synaptosome – membrane – plasma membrane – acrosomal vesicle – basement membrane – cell-cell junction – membrane fraction – membrane raft

Quelle: NCBI Entrez Gene, Gene Ontology