Die folgenden Gennamen und Gensymbole werden für Antigen Integrin alpha X über verschiedene Spezies hinweg verwendet:

integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5), integrin alpha X (Itgax)

Zu den weiteren Synonymen zählen:

CD11C, SLEB6, BR, GPIa, CD49B, VLA-2, VLAA2, VL3A, CD49C, GAPB3, MSK18, VCA-2, VLA3a, GAP-B3, FLJ34631, FLJ34704, IA4, CD49D, MGC90518, FNRA, CD49e, VLA5A, ITGAX, RGD1561123, Cr4, N418, Cd11c, AI449405, CD11c

Auf Proteinebene tauchen folgende Bezeichner für Antigen Integrin alpha X auf:

integrin alpha X – leu M5, alpha subunit – p150 95 integrin alpha chain – myeloid membrane antigen, alpha subunit – leukocyte surface antigen p150,95, alpha subunit – integrin, alpha X (antigen CD11C (p150), alpha polypeptide) – integrin alpha 2 – platelet antigen Br – platelet glycoprotein Ia – platelet glycoprotein GPIa – very late activation protein 2 receptor, alpha-2 subunit – integrin alpha 3 – galactoprotein B3 – antigen identified by monoclonal antibody J143 – very late activation protein 3 receptor, alpha-3 subunit – integrin alpha 4 – 269C wild type – integrin alpha-4 subunit – antigen CD49D, alpha-4 subunit of VLA-4 receptor – very late activation protein 4 receptor, alpha 4 subunit – integrin alpha 5 – fibronectin receptor, alpha subunit – very late activation protein 5, alpha subunit – integrin, alpha X (complement component 3 receptor 4 subunit) – integrin alpha-X – integrin aX – complement receptor 4 – CD11C (p150) alpha polypeptide – CD11 antigen-like family member C – leukocyte adhesion receptor p150,95 – leukocyte adhesion glycoprotein p150,95 alpha chain

Integrin alpha X erfüllt eine Reihe von Funktionen:

calcium ion binding – magnesium ion binding – protein binding – receptor activity – collagen binding – identical protein binding – integrin binding

Integrin alpha X spielt in den folgenden Prozessen eine Rolle:

cell adhesion – integrin-mediated signaling pathway – organ morphogenesis – blood coagulation – cell-matrix adhesion – interspecies interaction between organisms – B cell differentiation – leukocyte adhesion – cell-cell adhesion mediated by integrin – cell-substrate junction assembly – heterophilic cell adhesion – memory – wound healing, spreading of epidermal cells – activated T cell proliferation

Integrin alpha X ist wie folgt lokalisiert:

external side of plasma membrane – integral to membrane – integrin complex – membrane – plasma membrane – cell surface – cell-cell junction – focal adhesion – ruffle membrane – synaptosome

Quelle: NCBI Entrez Gene, Gene Ontology