Die folgenden Gennamen und Gensymbole werden für Antigen Inositol Polyphosphate-5-Phosphatase, 145kDa über verschiedene Spezies hinweg verwendet:

inositol polyphosphate-5-phosphatase, 145kDa (INPP5D), Inositol Polyphosphate 5-Phosphatase (ipp-5), inositol polyphosphate-5-phosphatase, 145kDa (inpp5d), inositol polyphosphate 5-phosphatase (EHI_159880), inositol polyphosphate 5-phosphatase (EHI_153490), phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (inpp5d), Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (ship1)

Zu den weiteren Synonymen zählen:

SHIP, SHIP1, hp51CN, SIP-145, MGC104855, MGC142140, MGC142142, INPP5D, MGC157261, inpp5d, ship, ship1, MGC68993

Auf Proteinebene tauchen folgende Bezeichner für Antigen Inositol Polyphosphate-5-Phosphatase, 145kDa auf:

SH2 containing inositol phosphatase – p150Ship – SH2 containing inositol phosphatase, isoform b – signaling inositol polyphosphate 5 phosphatase SIP-145 – inositol polyphosphate-5-phosphatase, 145kDa – phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like – Inositol Polyphosphate 5-Phosphatase family member (ipp-5) – inositol polyphosphate 5-phosphatase – phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 – SH2 domain-containing inositol-5'-phosphatase 1 – Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1

Inositol Polyphosphate-5-Phosphatase, 145kDa erfüllt eine Reihe von Funktionen:

SH3 domain binding – hydrolase activity – inositol or phosphatidylinositol phosphatase activity – inositol-polyphosphate 5-phosphatase activity – protein binding

Inositol Polyphosphate-5-Phosphatase, 145kDa spielt in den folgenden Prozessen eine Rolle:

apoptosis – immune response – phosphate metabolic process – signal transduction – epidermal growth factor receptor signaling pathway – inositol phosphate-mediated signaling – ovulation – phosphatidylinositol dephosphorylation

Inositol Polyphosphate-5-Phosphatase, 145kDa ist wie folgt lokalisiert:

cytoplasm – cytosol – extrinsic to membrane – membrane

Quelle: NCBI Entrez Gene, Gene Ontology