Die folgenden Gennamen und Gensymbole werden für Antigen Indoleamine 2,3-Dioxygenase 1 über verschiedene Spezies hinweg verwendet:

indoleamine 2,3-dioxygenase 1 (ido1), indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 1 (Ido1)

Zu den weiteren Synonymen zählen:

ido, indo, IDO1, IDO, INDO, CD107B, Ido, Indo, cd107b, MGC79476, MGC179467

Auf Proteinebene tauchen folgende Bezeichner für Antigen Indoleamine 2,3-Dioxygenase 1 auf:

indoleamine 2,3-dioxygenase 1 – indole 2,3-dioxygenase – indoleamine-pyrrole 2,3 dioxygenase – OTTMUSP00000022551 – indoleamine 23-dioxygenase – proto-IDO – putative indoleamine 2,3-dioxygenase

Indoleamine 2,3-Dioxygenase 1 erfüllt eine Reihe von Funktionen:

electron carrier activity – heme binding – indoleamine 2,3-dioxygenase activity – metal ion binding – oxidoreductase activity – tryptophan 2,3-dioxygenase activity – iron ion binding – oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen – amino acid binding – oxygen binding

Indoleamine 2,3-Dioxygenase 1 spielt in den folgenden Prozessen eine Rolle:

NAD metabolic process – female pregnancy – oxidation reduction – positive regulation of T cell tolerance induction – positive regulation of T-helper 2 type immune response – positive regulation of chronic inflammatory response – tryptophan catabolic process to kynurenine – behavior – cytokine production during acute inflammatory response – defense response – kynurenic acid biosynthetic process – multicellular organismal response to stress – negative regulation of T cell apoptosis – negative regulation of T cell proliferation – negative regulation of activated T cell proliferation – negative regulation of interleukin-10 production – positive regulation of interleukin-12 production – response to lipopolysaccharide

Indoleamine 2,3-Dioxygenase 1 ist wie folgt lokalisiert:

cytoplasm – cytosol – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology