Die folgenden Gennamen und Gensymbole werden für Antigen IKAROS Family Zinc Finger 1 über verschiedene Spezies hinweg verwendet:

IKAROS family zinc finger 1 (Ikaros) (IKZF1), IKAROS family zinc finger 1 (Ikzf1), IKAROS family zinc finger 1 (Ikaros) (ikzf1)

Zu den weiteren Synonymen zählen:

IK1, LYF1, hIk-1, IKAROS, PRO0758, ZNFN1A1, Hs.54452, RGD1562979, ikaros, znfn1a1, MGC152552, ik1, lyf1, hik-1, pro0758, hs.54452, MGC108252

Auf Proteinebene tauchen folgende Bezeichner für Antigen IKAROS Family Zinc Finger 1 auf:

zinc finger protein, subfamily 1A, 1 (Ikaros) – CLL-associated antigen KW-6 – Ikaros (zinc finger protein) – IKAROS family zinc finger 1 – DNA-binding protein Ikaros – Ikaros transcription factor – ikaros family zinc finger protein 1 – IKAROS family zinc finger 1 (Ikaros) – KAROS family zinc finger 1 (Ikaros) – DNA-binding protein Ikaros-like

IKAROS Family Zinc Finger 1 erfüllt eine Reihe von Funktionen:

DNA binding – metal ion binding – zinc ion binding – promoter binding – protein binding – protein heterodimerization activity – sequence-specific DNA binding – specific transcriptional repressor activity – transcription factor activity – transcription repressor activity – ATP binding – aminoacyl-tRNA ligase activity – nucleic acid binding – nucleotide binding – sequence-specific DNA binding transcription factor activity

IKAROS Family Zinc Finger 1 spielt in den folgenden Prozessen eine Rolle:

mesoderm development – regulation of transcription – B cell differentiation – Peyer's patch development – T cell differentiation – forebrain development – gland development – hemopoiesis – lymph node development – natural killer cell differentiation – negative regulation of cellular transcription – negative regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of NK T cell differentiation – positive regulation of cellular transcription – positive regulation of multicellular organism growth – positive regulation of neutrophil differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of cellular transcription, DNA-dependent – retina development in camera-type eye – thymus development – T cell differentiation in the thymus – tRNA aminoacylation for protein translation – translation – multicellular organismal development – negative regulation of transcription – positive regulation of transcription – regulation of transcription, DNA-dependent

IKAROS Family Zinc Finger 1 ist wie folgt lokalisiert:

intracellular – nucleus – centromeric heterochromatin – cytoplasm

Quelle: NCBI Entrez Gene, Gene Ontology