Die folgenden Gennamen und Gensymbole werden für Antigen Huntingtin Interacting Protein 1 über verschiedene Spezies hinweg verwendet:

huntingtin interacting protein 1 (HIP1), Huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (Hip1), SET domain containing 2 (SETD2), huntingtin interacting protein 1 (hip1)

Zu den weiteren Synonymen zählen:

ILWEQ, MGC126506, CG10971, DmelCG10971, KIAA4113, MGC27616, mKIAA4113, 2610109B09Rik, A930014B11Rik, E130315I21Rik, HYPB, SET2, HIF-1, KMT3A, HBP231, HSPC069, p231HBP, FLJ16420, FLJ22472, FLJ23184, FLJ45883, FLJ46217, KIAA1732, hip1, MGC78813, HIP1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Huntingtin Interacting Protein 1 auf:

huntingtin interacting protein 1 – huntingtin interacting protein 1, isoform A – CG10971-PA – Hip1-PA – huntingtin interacting protein 1, isoform B – CG10971-PB – Hip1-PB – SET domain containing 2 – huntingtin yeast partner B – lysine N-methyltransferase 3A – SET domain-containing protein 2 – huntingtin-interacting protein B – histone-lysine N-methyltransferase SETD2 – huntingtin-interacting protein 1

Huntingtin Interacting Protein 1 erfüllt eine Reihe von Funktionen:

actin binding – clathrin binding – phosphoinositide binding – structural constituent of cytoskeleton – phospholipid binding – protein binding – DNA binding – histone-lysine N-methyltransferase activity – methyltransferase activity – oxidoreductase activity – transferase activity – transition metal ion binding – binding

Huntingtin Interacting Protein 1 spielt in den folgenden Prozessen eine Rolle:

activation of caspase activity – cell death – cell differentiation – clathrin coat assembly – endocytosis – induction of apoptosis – positive regulation of receptor-mediated endocytosis – regulation of apoptosis – regulation of transcription – cytoskeleton organization – apoptosis – transcription – chromatin modification

Huntingtin Interacting Protein 1 ist wie folgt lokalisiert:

Golgi apparatus – clathrin coated vesicle membrane – cytoplasm – cytoplasmic vesicle – cytoskeleton – endomembrane system – membrane – membrane fraction – nucleus – clathrin-coated vesicle – clathrin coat – integral to membrane

Quelle: NCBI Entrez Gene, Gene Ontology