Die folgenden Gennamen und Gensymbole werden für Antigen Hsp70 über verschiedene Spezies hinweg verwendet:

heat shock cognate 70-kd protein (hsp70), Hsp70Bbb (Hsp70Bbb), heat shock 70kDa protein (hsp70), heat shock protein 70 (HSP70), HSP70 protein (HSP70), heat shock protein 70 (hsp70), heat shock protein 70 (Hsp70), HSP70-LIKE PROTEIN (MITOCHONDRIAL TYPE) (hsp70), heat shock protein homologue (hsp70), heat shock protein 78 (hsp70), chaperone HSP70 (hsp70), heat shock protein 70, putative chloroplast precursor (HSP70)

Zu den weiteren Synonymen zählen:

hspa1a, hsp70-4, CG31354, HSP70, Hsp70Bb, hsp70B, hsp70Bb-prime, DmelCG5834, CG5834, xhsp70, HSPA1, hsp70, Hsp70

Auf Proteinebene tauchen folgende Bezeichner für Antigen Hsp70 auf:

heat shock cognate 70-kd protein – etID309743.10 – stress protein HSP70 – heat shock 70kD protein 1A – Hsp70Bbb – CG5834-PA – Hsp70Bbb-PA – heat shock 70 kDa protein – hsp 70 protein – heat shock protein – heat shock 70 kDa protein 1 – HSP70 protein – heat shock protein 70 – down-regulated by high concentrations of aluminum – heat shock cognate 70 – HSP70-LIKE PROTEIN (MITOCHONDRIAL TYPE) – heat shock protein homologue – heat shock protein 78 – chaperone HSP70 – heat shock protein 70, putative chloroplast precursor – heat shock 70kDa protein

Hsp70 erfüllt eine Reihe von Funktionen:

ATP binding – nucleotide binding – nucleoside-triphosphatase activity – serine-type endopeptidase activity – unfolded protein binding

Hsp70 spielt in den folgenden Prozessen eine Rolle:

camera-type eye morphogenesis – response to cadmium ion – response to heat – response to stress – response to xenobiotic stimulus – heat shock-mediated polytene chromosome puffing – response to hypoxia – protein folding – proteolysis

Hsp70 ist wie folgt lokalisiert:

lipid particle – mitochondrial endopeptidase Clp complex

Quelle: NCBI Entrez Gene, Gene Ontology