Die folgenden Gennamen und Gensymbole werden für Antigen Homocitrate Synthase über verschiedene Spezies hinweg verwendet:

ATP citrate lyase (ACLY), citrate synthase (CS), ATP citrate lyase (Acly), ATP citrate lyase (ATPCL), citrate synthase (Cs), ATP citrate lyase a (aclya), ATP citrate lyase (acly), ATP-citrate synthase (AaeL_AAEL004297), citrate synthase, mitochondrial (CpipJ_CPIJ010291), ATP-citrate synthase (Bm1_26245), atp-citrate synthase (ACL)

Zu den weiteren Synonymen zählen:

ACL, ATPCL, CLATP, Clatp, MGC124629, anon-WO0140519.179, BcDNA:LD21334, CG8322, DmATPCL, DmelCG8322, l(2)01466, l(2)k09217, n(2)k09217, AW538652, A730098H14Rik, acly, cb722, zgc:92008, ACLY, MGC128987

Auf Proteinebene tauchen folgende Bezeichner für Antigen Homocitrate Synthase auf:

ATP citrate lyase – OTTHUMP00000164773 – citrate synthase – citrate synthase, mitochondrial – ATP-citrate synthase – citrate cleavage enzyme – ATP-citrate (pro-S-)-lyase – ATP citrate lyase, isoform E – CG8322-PE – ATPCL-PE – ATP citrate lyase, isoform D – CG8322-PD – ATPCL-PD – ATP citrate lyase, isoform F – CG8322-PF – ATPCL-PF – OTTMUSP00000006599 – ATP-citrate lyase – atp-citrate synthase – ATP citrate synthase – ATP-citrate synthase-like

Homocitrate Synthase erfüllt eine Reihe von Funktionen:

ATP binding – ATP citrate synthase activity – citrate (pro-3S)-lyase activity – magnesium ion binding – nucleotide binding – protein binding – succinate-CoA ligase (ADP-forming) activity – transferase activity – citrate (Si)-synthase activity – binding – catalytic activity – lyase activity – metal ion binding – transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Homocitrate Synthase spielt in den folgenden Prozessen eine Rolle:

ATP catabolic process – cellular carbohydrate metabolic process – citrate metabolic process – coenzyme A metabolic process – lipid biosynthetic process – metabolic process – tricarboxylic acid cycle – acetyl-CoA biosynthetic process – lipid metabolic process – acetyl-CoA metabolic process – carbohydrate metabolic process – oxaloacetate metabolic process

Homocitrate Synthase ist wie folgt lokalisiert:

citrate lyase complex – cytoplasm – cytosol – mitochondrial matrix – mitochondrion – lipid particle – intracellular – phagocytic vesicle

Quelle: NCBI Entrez Gene, Gene Ontology