Die folgenden Gennamen und Gensymbole werden für Antigen Histone Deacetylase 2 über verschiedene Spezies hinweg verwendet:

histone deacetylase 2 (HDAC2), histone deacetylase 2 (Hdac2)

Zu den weiteren Synonymen zählen:

RPD3, YAF1, Yy1bp, mRPD3, D10Wsu179e

Auf Proteinebene tauchen folgende Bezeichner für Antigen Histone Deacetylase 2 auf:

histone deacetylase 2 – YY1-associated factor 1 – transcriptional regulator homolog RPD3 – HD2 – OTTMUSP00000022803 – YY1 transcription factor-binding protein – histone deacetylase-2

Histone Deacetylase 2 erfüllt eine Reihe von Funktionen:

enzyme binding – histone deacetylase activity – hydrolase activity – sequence-specific DNA binding – specific transcriptional repressor activity – transcription activator activity – transcription factor activity – transcription factor binding – heat shock protein binding – protein binding – sequence-specific DNA binding transcription factor activity – protein deacetylase activity

Histone Deacetylase 2 spielt in den folgenden Prozessen eine Rolle:

chromatin remodeling – histone deacetylation – maintenance of chromatin silencing – negative regulation of MHC class II biosynthetic process – negative regulation of cell cycle – negative regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of transcription factor activity – positive regulation of cell proliferation – positive regulation of collagen biosynthetic process – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of proteolysis – positive regulation of receptor biosynthetic process – regulation of transcription – chromatin modification – hippocampus development – negative regulation of neuron projection development – negative regulation of transcription – neuron differentiation – transcription – cellular response to heat – response to cocaine – response to drug

Histone Deacetylase 2 ist wie folgt lokalisiert:

NuRD complex – Sin3 complex – cytoplasm – heterochromatin – nucleus – replication fork – chromatin – ESC/E(Z) complex – histone deacetylase complex

Quelle: NCBI Entrez Gene, Gene Ontology