Die folgenden Gennamen und Gensymbole werden für Antigen Histone Deacetylase 1 über verschiedene Spezies hinweg verwendet:

histone deacetylase 1 (HDAC1), histone deacetylase 1 pseudogene (Gm10093), Rpd3 (Rpd3), histone deacetylase (HDAC1), histone deacetylase 1 (hdac1), histone deacetylase 2 (hdac2), histone deacetylase 1-like (Hdac1l), histone deacetylase 1 (Hdac1), HD1 (HISTONE DEACETYLASE 1); basal transcription repressor/ histone deacetylase/ protein binding (HD1)

Zu den weiteren Synonymen zählen:

HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, Hdac1, Gm1824, EG15181, Hdac1-ps, ENSMUSG00000061062, CG7471, dHDAC-1, dHDAC1, DHDAC1, DmelCG7471, dmHDA401, DmHDAC1, drpd3, dRpd3, dRPD3, DRpd3, E(var)3-64BC, HDAC, HDAC-1, hdac1, HDAC1, l(3)04556, l(3)64Cc, rpd3, Rpd3/HDAC, rpd[3], Su(var)3-26, Su(var)326, Su(var)328, hdac1b, MGC53583, Rpd3, GB14706, yaf1, MGC69271, MGC81850, gon-10, rpd3l1, hdac1-b, MGC69289, hdac-1, MGC101582, chunp6919, zgc:65818, wu:fb19h11, wu:fi06f03, zgc:101582, mp:zf637-2-001987, MGC127235, MommeD5, MGC102534, MGC118085, ARABIDOPSIS HISTONE DEACETYLASE 1, ATHD1, ATRPD3A, F20D10.250, F20D10_250, HDA1, HDA19, HISTONE DEACETYLASE, HISTONE DEACETYLASE 1, HISTONE DEACETYLASE 19, HISTONE DEACETYLASE19, RPD3A, DKFZp468K082

Auf Proteinebene tauchen folgende Bezeichner für Antigen Histone Deacetylase 1 auf:

histone deacetylase 1 – reduced potassium dependency, yeast homolog-like 1 – Rpd3 – CG7471-PA – Rpd3-PA – reduced potassium dependency 3 – Rpd3 histone deacetylase – histone deacetylase 1 (HDAC1) – suppressor of variegation 326 – histone deacetylase – histone deacetylase 1 b – histone deacetylase 2 – histone deacetylase 1-B – col – colgate – HD1 – OTTMUSP00000010171 – HD1 (HISTONE DEACETYLASE 1); basal transcription repressor/ histone deacetylase/ protein binding

Histone Deacetylase 1 erfüllt eine Reihe von Funktionen:

enzyme binding – histone deacetylase activity – hydrolase activity – identical protein binding – transcription activator activity – transcription factor activity – transcription factor binding – protein binding – transcription corepressor activity – DNA binding – chromatin binding – molecular_function – sequence-specific DNA binding transcription factor activity – histone deacetylase binding – protein complex binding – protein deacetylase activity – specific transcriptional repressor activity – transcription repressor activity – basal transcription repressor activity

Histone Deacetylase 1 spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – chromatin remodeling – histone deacetylation – interspecies interaction between organisms – negative regulation of cell cycle – negative regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of myotube differentiation – positive regulation of cell proliferation – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of receptor biosynthetic process – regulation of transcription – blastoderm segmentation – chromatin silencing – dendrite morphogenesis – determination of adult lifespan – gene silencing – muscle organ development – negative regulation of transcription – oogenesis – respiratory electron transport chain – tricarboxylic acid cycle – biological_process – chromatin modification – endoderm development – hippocampus development – neuron differentiation – Wnt receptor signaling pathway – convergent extension involved in axis elongation – determination of dorsal identity – digestive tract development – exocrine pancreas development – facial nucleus development – hemopoietic stem cell differentiation – liver development – melanocyte differentiation – negative regulation of cell proliferation – neuron migration – oligodendrocyte differentiation – positive regulation of neurogenesis – rostrocaudal neural tube patterning – cellular response to oxidative stress – histone H3 deacetylation – histone H4 deacetylation – negative regulation by host of viral transcription – negative regulation of neuron apoptosis – protein amino acid deacetylation – response to drug – transcription – DNA mediated transformation – histone acetylation – jasmonic acid and ethylene-dependent systemic resistance – regulation of multicellular organismal development

Histone Deacetylase 1 ist wie folgt lokalisiert:

NuRD complex – Sin3 complex – cytoplasm – cytosol – nucleus – ESC/E(Z) complex – Myb complex – chromatin – polytene chromosome interband – cellular_component – heterochromatin – neuronal cell body – nucleoplasm – histone deacetylase complex – protein complex

Quelle: NCBI Entrez Gene, Gene Ontology