Die folgenden Gennamen und Gensymbole werden für Antigen Hexose-6-Phosphate Dehydrogenase über verschiedene Spezies hinweg verwendet:

glucose-6-phosphate dehydrogenase (G6PD), glucose-6-phosphate dehydrogenase (G6pd), Zwischenferment (Zw), glucose-6-phosphate dehydrogenase (g6pd), glucose-6-phosphate dehydrogenase (MM_2824), glucose-6-phosphate 1-dehydrogenase (g6pD), glucose-6-P dehydrogenase (LACBIDRAFT_188936), Zwischenferment (Dsim\Zw), glucose-6-phosphate 1-dehydrogenase (G6PD) (zwf), Glucose-6-phosphate 1-dehydrogenase (g6pd)

Zu den weiteren Synonymen zählen:

G6PD1, G6pdx, G-6-PD, G-6-pdh, G-6PD, G6-pd, G6PD, G6PDH, DmelCG12529, CG12529, g6pdh, MGC69058, g6pd2, fj78b06, wu:fj78b06, si:dkey-90a13.8, G6pd, Dsim\G6pd, Dsim\G6pdh, dsim_GLEANR_8868, Dsim\GD24877, GD24877, Zw, g6pd

Auf Proteinebene tauchen folgende Bezeichner für Antigen Hexose-6-Phosphate Dehydrogenase auf:

glucose-6-phosphate dehydrogenase – glucose-6-phosphate 1-dehydrogenase – glucose-6-phosphate dehydrogenase, G6PD – glucose-6-phosphate dehydrogenase X-linked – zwischenferment, isoform A – CG12529-PA – Zw-PA – Glucose-6-phosphate DH – glucose-6-phosphate 1dehydrogenase – zwischenferment, isoform B – CG12529-PB – Zw-PB – glucose-6-phosphate dehydrogenase 2 – glucose-6-P dehydrogenase – Dsim\GD24877-PA – Dsim\Zw-PA – GD24877-PA – zwischenferment – glucose-6-phosphate 1-dehydrogenase (G6PD) – Glucose-6-phosphate 1-dehydrogenase

Hexose-6-Phosphate Dehydrogenase erfüllt eine Reihe von Funktionen:

NADP or NADPH binding – binding – glucose binding – glucose-6-phosphate dehydrogenase activity – oxidoreductase activity – protein homodimerization activity – sugar binding

Hexose-6-Phosphate Dehydrogenase spielt in den folgenden Prozessen eine Rolle:

carbohydrate metabolic process – cellular response to oxidative stress – cholesterol biosynthetic process – cytokine production – erythrocyte maturation – glucose 6-phosphate utilization – glucose metabolic process – glutathione metabolic process – lipid metabolic process – negative regulation of protein amino acid glutathionylation – oxidation reduction – pentose biosynthetic process – pentose-phosphate shunt, oxidative branch – ribose phosphate biosynthetic process – NADP biosynthetic process – NADPH regeneration – angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure – erythrocyte development – glucose 6-phosphate metabolic process – interleukin-10 production – interleukin-12 production – pentose-phosphate shunt – regulation of anti-apoptosis – regulation of multicellular organism growth – response to ethanol – response to food – response to organic cyclic substance – response to oxidative stress – vasodilation by angiotensin involved in regulation of systemic arterial blood pressure

Hexose-6-Phosphate Dehydrogenase ist wie folgt lokalisiert:

centrosome – cytoplasm – cytosol – internal side of plasma membrane – intracellular membrane-bounded organelle – microsome – nucleus – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology