Die folgenden Gennamen und Gensymbole werden für Antigen Heat Shock Protein 8 über verschiedene Spezies hinweg verwendet:

heat shock protein A8 (Hspa8), Heat shock protein cognate 3 (Hsc70-3), Heat shock protein cognate 5 (Hsc70-5), Heat shock protein cognate 1 (Hsc70-1), Hsc70Cb, isoform A (Hsc70Cb), Heat shock protein cognate 2 (Hsc70-2), heat shock 70kDa protein 8 (HSPA8), heat shock 70kDa protein 1-like (hspa1l), heat shock protein 8 (hspa8), HSC70-1 (HEAT SHOCK COGNATE PROTEIN 70-1); ATP binding (HSC70-1), Heat shock protein cognate 6 (Hsc70-6), DyakGE24282-PA (DyakHsc70-4), DsimGD18998-PA (DsimHsc70-4), heat shock protein 70 cognate (hsc70), heat shock cognate 70 (HSC70), heat shock protein 70 (hsc70), heat shock protein cognate 70 (hsc70)

Zu den weiteren Synonymen zählen:

Hsc70, MGC114311, BiP, CG1579, Grp78, HSC-70, HSC3, HSC70, Hsc3p, anon-WO0138581.7, dhsc70, dmHsc72, hsc70-3, hsc72, l(1)G0102, l(1)G0111, l(1)G0292, l(1)G0341, l(1)G0407, l(1)G0466, DmelCG4147, CG4147, HSC5, l(2)k04907, DmelCG8542, CG8542, 143191_at, BcDNA:RH49358, HSC1, DmelCG8937, CG8937, 0041/12, 0318/20, 1342/17, 1348/02, 1485/13, BEST:LD32772, LD32772, anon-WO0118547.302, hsc70Cb, l(3)00082, l(3)07621, l(3)134217, l(3)148513, l(3)70Ca, l(3)70Cb, l(3)S134217, l(3)S134802, l(3)S148513, DmelCG6603, CG6603, HSC2, Hsc70.2, DmelCG7756, CG7756, HSPA10, MGC128130, hsc70, hsc70.I, MGC52655, MGC55272, wu:fb01g06, wu:fi48b06, ARABIDOPSIS THALIANA HEAT SHOCK COGNATE PROTEIN 70-1, AT-HSC70-1, HEAT SHOCK COGNATE PROTEIN 70, HEAT SHOCK COGNATE PROTEIN 70-1, HEAT SHOCK PROTEIN 70-1, HSC70-1, HSP70-1, T22P11.90, T22P11_90, hsc6, dyak_GLEANR_7992, DyakGE24282, GE24282, Hsc70-4, dsim_GLEANR_2803, DsimGD18998, GD18998, hspa1l, NV11212

Auf Proteinebene tauchen folgende Bezeichner für Antigen Heat Shock Protein 8 auf:

heat shock cognate 71 kDa protein – heat shock protein 8 – heat shock 70kD protein 8 – heat shock 70 kDa protein 8 – Heat shock cognate protein 70 – heat shock protein cognate 3, isoform B – CG4147-PB – Hsc70-3-PB – immunoglobulin binding protein – heat shock cognate protein 3 – heat shock protein cognate 3, isoform D – CG4147-PD – Hsc70-3-PD – heat shock protein cognate 3, isoform A – CG4147-PA – Hsc70-3-PA – heat shock protein cognate 3, isoform C – CG4147-PC – Hsc70-3-PC – heat shock protein cognate 5 – CG8542-PA – Hsc70-5-PA – heat shock protein cognate 1, isoform C – CG8937-PC – Hsc70-1-PC – heat shock protein cognate 1, isoform A – CG8937-PA – Hsc70-1-PA – heat shock protein cognate 1, isoform D – CG8937-PD – Hsc70-1-PD – Hsc70Cb, isoform A – CG6603-PA – Hsc70Cb-PA – Hsc70Cb, isoform B – CG6603-PB – Hsc70Cb-PB – Hsc70Cb, isoform C – CG6603-PC – Hsc70Cb-PC – heat shock protein cognate 2 – CG7756-PA – Hsc70-2-PA – Hsc70 ATPase – heat shock cognate 71 kD protein – heat shock 70kd protein 10 (HSC71) – heat shock 70kDa protein 1-like – heat shock cognate protein 70 – heat shock 70kDa protein 8 – heat shock cognate 71-kd protein – HSC70-1 (HEAT SHOCK COGNATE PROTEIN 70-1); ATP binding – DyakGE24282-PA – DyakHsc70-4-PA – GE24282-PA – Hsc70-4 – Hsc70-4-PA – DsimGD18998-PA – DsimHsc70-4-PA – GD18998-PA – hsc70.1 – heat shock cognate 70 – heat shock protein 70 – heat shock protein cognate 70

Heat Shock Protein 8 erfüllt eine Reihe von Funktionen:

ADP binding – ATP binding – ATPase activity, coupled – nucleotide binding – protein binding – receptor binding – unfolded protein binding – ATPase activity – chaperone binding

Heat Shock Protein 8 spielt in den folgenden Prozessen eine Rolle:

ATP catabolic process – cellular membrane organization – chaperone mediated protein folding requiring cofactor – chaperone-mediated protein folding – post-Golgi vesicle-mediated transport – protein folding – regulation of cell cycle – response to stress – RNA interference – response to heat – sleep – response to cadmium ion – response to cold – response to virus

Heat Shock Protein 8 ist wie folgt lokalisiert:

cell surface – cytoplasm – cytosol – extracellular vesicular exosome – intracellular – melanosome – protein complex – ribonucleoprotein complex – endoplasmic reticulum – lipid particle – mitochondrion – apoplast – cell wall – chloroplast – cytosolic ribosome – membrane – nucleolus – nucleus – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology