Die folgenden Gennamen und Gensymbole werden für Antigen Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) über verschiedene Spezies hinweg verwendet:

heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5), 78 kDa glucose-regulated protein (CpipJ_CPIJ003550), 78 kDa glucose-regulated protein (grp78), BiP/GRP78 (LOC100533358), glucose-regulated protein 78 (BiP/grp78), glucose-regulated protein 78 (Tc00.1047053506585.40), glucose-regulated protein 78 (Tb11.02.5450), glucose-regulated protein 78 (Tb11.02.5500), glucose-regulated protein 78 (LmjF28.1200), heat shock 70kDa protein 5 (HSPA5), BIP (KAR2), glucose-regulated protein 78kDa (grp78), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (hspa5)

Zu den weiteren Synonymen zählen:

BIP, MIF2, GRP78, FLJ26106, HSPA5, DKFZp459C013, BiP, GRP-78, BiP/grp78, hspa5, MGC52648

Auf Proteinebene tauchen folgende Bezeichner für Antigen Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) auf:

heat shock 70kDa protein 5 – Heat-shock 70kD protein-5 (glucose-regulated protein, 78kD) – heat shock 70kD protein 5 (glucose-regulated protein, 78kD) – 78 kDa glucose-regulated protein – heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) – Protein 1603 – glucose-regulated protein 78 – glucose-regulated protein, 78kDa – BIP – Kar2p – glucose-regulated protein 78kDa

Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) erfüllt eine Reihe von Funktionen:

ATP binding – calcium ion binding – caspase inhibitor activity – nucleotide binding – protein binding, bridging – ribosome binding – unfolded protein binding – molecular_function – ATPase activity

Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) spielt in den folgenden Prozessen eine Rolle:

ER overload response – anti-apoptosis – cellular response to glucose starvation – negative regulation of caspase activity – SRP-dependent cotranslational protein targeting to membrane – protein folding – ER-associated protein catabolic process – ER-nucleus signaling pathway – SRP-dependent cotranslational protein targeting to membrane, translocation – karyogamy involved in conjugation with cellular fusion – posttranslational protein targeting to membrane, translocation – response to stress – response to unfolded protein

Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) ist wie folgt lokalisiert:

ER-Golgi intermediate compartment – caspase complex – cell surface – endoplasmic reticulum – endoplasmic reticulum lumen – integral to endoplasmic reticulum membrane – melanosome – nucleus – perinuclear region of cytoplasm – luminal surveillance complex

Quelle: NCBI Entrez Gene, Gene Ontology