Die folgenden Gennamen und Gensymbole werden für Antigen Heart and Neural Crest Derivatives Expressed 1 über verschiedene Spezies hinweg verwendet:

heart and neural crest derivatives expressed 1 (HAND1), heart and neural crest derivatives expressed 1 (Hand1), heart and neural crest derivatives expressed 1 (hand1-A), heart and neural crest derivatives expressed 1 (hand1), eHAND basic helix-loop-helix transcription factor (EHAND)

Zu den weiteren Synonymen zählen:

Hxt, eHand, Thing1, bHLHa27, MGC114332, hand1-A, eHAND, HAND1, HXT, hand1, hxt, hand-1, thing1, EHAND, Hand1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Heart and Neural Crest Derivatives Expressed 1 auf:

basic helix-loop-helix transcription factor HAND1 – heart- and neural crest derivatives-expressed protein 1 – heart and neural crest derivatives expressed transcript 1 – extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 – heart and neural crest derivatives expressed 1 – heart and neural crest derivatives-expressed protein 1 – eHAND – eHAND basic helix-loop-helix transcription factor – Heart- and neural crest derivatives-expressed protein 1

Heart and Neural Crest Derivatives Expressed 1 erfüllt eine Reihe von Funktionen:

bHLH transcription factor binding – promoter binding – protein heterodimerization activity – protein homodimerization activity – transcription coactivator activity – transcription factor activity – transcription repressor activity – DNA binding – enzyme binding – protein binding – sequence-specific DNA binding transcription factor activity – transcription factor binding – transcription regulator activity

Heart and Neural Crest Derivatives Expressed 1 spielt in den folgenden Prozessen eine Rolle:

angiogenesis – blastocyst development – embryonic heart tube development – embryonic placenta development – heart looping – heart septum morphogenesis – mesoderm formation – multicellular organismal development – negative regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of gene-specific transcription from RNA polymerase II promoter – regulation of transcription – trophectodermal cell differentiation – ventricular cardiac muscle morphogenesis – cardiac left ventricle formation – cardiac right ventricle formation – cardiac septum morphogenesis – cell differentiation – heart development – in utero embryonic development – negative regulation of transcription from RNA polymerase II promoter – positive regulation of transcription from RNA polymerase II promoter – positive regulation of transcription, DNA-dependent – transcription from RNA polymerase II promoter – trophoblast giant cell differentiation – ventricular cardiac muscle tissue morphogenesis

Heart and Neural Crest Derivatives Expressed 1 ist wie folgt lokalisiert:

cytoplasm – nucleus – nucleolus – nucleoplasm

Quelle: NCBI Entrez Gene, Gene Ontology