Die folgenden Gennamen und Gensymbole werden für Antigen HOP Homeobox über verschiedene Spezies hinweg verwendet:

HOP homeobox (Hopx), HOP homeobox (HOPX), homeodomain-only protein (HOP), Homeodomain-only protein (hop), HOP homeobox (hopx)

Zu den weiteren Synonymen zählen:

Hod, Hop, Ob1, Obl, Hdop, Toto, Cameo, AI848177, AW490897, 1110018K11Rik, 1200015P04Rik, 2300002F06Rik, HOD, HOP, OB1, LAGY, TOTO, CAMEO, NECC1, SMAP31, MGC20820, GIIg15b, HOPX, hop, hod, ob1, lagy, toto, cameo, necc1, smap31, MGC147344

Auf Proteinebene tauchen folgende Bezeichner für Antigen HOP Homeobox auf:

homeodomain-only protein – mOB1 – odd homeobox 1 – OTTMUSP00000032809 – homeobox only domain – homeobox-only protein – odd homeobox protein 1 – homeodomain only protein – HOP homeobox – odd homeobox 1 protein – lung cancer-associated Y protein – not expressed in choriocarcinoma clone 1 – global ischemia-induced protein 15B – global ischemia induced protein GIIG15B – global ischemia-induced gene 15B protein – Homeodomain-only protein

HOP Homeobox erfüllt eine Reihe von Funktionen:

DNA binding – protein binding – sequence-specific DNA binding – sequence-specific DNA binding transcription factor activity – transcription repressor activity – transcription factor activity

HOP Homeobox spielt in den folgenden Prozessen eine Rolle:

heart development – histone deacetylation – lung alveolus development – multicellular organismal development – negative regulation of cell differentiation – negative regulation of transcription from RNA polymerase II promoter – positive regulation of skeletal muscle tissue regeneration – positive regulation of striated muscle cell differentiation – regulation of heart contraction – regulation of transcription – regulation of transcription, DNA-dependent – transcription – trophectodermal cell differentiation

HOP Homeobox ist wie folgt lokalisiert:

cytoplasm – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology