Die folgenden Gennamen und Gensymbole werden für Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A über verschiedene Spezies hinweg verwendet:

glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A), glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Grin2a), glutamate receptor, ionotropic, N-methyl D-aspartate 2A (Grin2a), glutamate receptor, ionotropic, N-methyl D-aspartate 2A (grin2a)

Zu den weiteren Synonymen zählen:

NR2A, NMDAR2A, GRIN2A, nr2a

Auf Proteinebene tauchen folgende Bezeichner für Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A auf:

N-methyl-D-aspartate receptor subunit 2A – OTTHUMP00000160135 – OTTHUMP00000174531 – NMDA receptor subtype 2A – N-methyl-D-aspartate receptor channel, subunit epsilon-1 – glutamate receptor, ionotropic, NMDA2A (epsilon 1) – GluRepsilon1 – OTTMUSP00000017426 – glutamate [NMDA] receptor subunit epsilon-1 – N-methyl D-aspartate receptor subtype 2A – glutamate receptor, ionotropic, N-methyl D-aspartate 2A – glutamate [NMDA] receptor subunit epsilon 1 – glutamate receptor, ionotropic, N-methyl-D-aspartate subunit 2A – N-methyl-D-aspartate receptor subunit NR2A – glutamate [NMDA] receptor subunit epsilon-1-like

Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A erfüllt eine Reihe von Funktionen:

N-methyl-D-aspartate selective glutamate receptor activity – calcium channel activity – calcium ion binding – extracellular-glutamate-gated ion channel activity – glutamate binding – magnesium ion binding – protein binding – receptor activity – cation channel activity – ion channel activity – ionotropic glutamate receptor activity – ATPase binding – cell adhesion molecule binding – glutamate receptor binding – metal ion binding – neurotransmitter binding – protein complex binding – protein kinase binding – transporter activity – voltage-gated cation channel activity – zinc ion binding

Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A spielt in den folgenden Prozessen eine Rolle:

calcium ion transport – directional locomotion – dopamine metabolic process – glutamate signaling pathway – ion transport – memory – negative regulation of protein catabolic process – neurogenesis – positive regulation of apoptosis – protein localization – regulation of excitatory postsynaptic membrane potential – regulation of sensory perception of pain – regulation of synaptic plasticity – response to amphetamine – response to drug – response to ethanol – response to wounding – serotonin metabolic process – sleep – startle response – visual learning – detection of mechanical stimulus involved in sensory perception of pain – learning – learning or memory – locomotion – locomotory behavior – regulation of membrane potential – regulation of postsynaptic membrane potential – sensory perception of pain – synaptic transmission – transport – calcium ion transmembrane transport – cellular response to amino acid stimulus – cellular response to dsRNA – cellular response to growth factor stimulus – cellular response to lipid – cellular response to magnesium ion – cellular response to manganese ion – cellular response to protein stimulus – cellular response to zinc ion – cerebral cortex development – hippocampus development – ion transmembrane transport – ionotropic glutamate receptor signaling pathway – positive regulation of cell death – regulation of action potential – regulation of long-term neuronal synaptic plasticity – regulation of synaptic transmission – response to amine stimulus – response to ammonium ion – response to calcium ion – response to carbohydrate stimulus – response to cocaine – response to fungicide – response to light stimulus – response to manganese ion – response to methylmercury – response to organic cyclic substance – response to other organism – rhythmic process – signal transduction – spinal cord development

Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A ist wie folgt lokalisiert:

N-methyl-D-aspartate selective glutamate receptor complex – cell junction – integral to plasma membrane – neuron projection – plasma membrane – postsynaptic density – postsynaptic membrane – presynaptic membrane – synapse – synaptosome – dendritic spine – integral to membrane – membrane – membrane fraction – flotillin complex – outer membrane-bounded periplasmic space – terminal button

Quelle: NCBI Entrez Gene, Gene Ontology