Die folgenden Gennamen und Gensymbole werden für Antigen Glutamate Receptor, Ionotrophic, AMPA 2/3 über verschiedene Spezies hinweg verwendet:

glutamate receptor, ionotropic, AMPA 1 (GRIA1), glutamate receptor, ionotropic, AMPA 2 (GRIA2), glutamate receptor, ionotropic, AMPA1 (alpha 1) (Gria1), glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2), glutamate receptor, ionotropic, AMPA 2 (Gria2), glutamate receptor, ionotropic, AMPA 1 (Gria1)

Zu den weiteren Synonymen zählen:

GLUH1, GLUR1, GLURA, HBGR1, MGC133252, GLUR2, GLURB, HBGR2, GluR-K2, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, GluA2, Glur2, GluR-B, Glur-2, GluR2, gluR-B, gluR-A

Auf Proteinebene tauchen folgende Bezeichner für Antigen Glutamate Receptor, Ionotrophic, AMPA 2/3 auf:

glutamate receptor, ionotropic, AMPA 1 – AMPA 1 – glutamate receptor, ionotropic, AMPA 2 – gluR-B – OTTHUMP00000165324 – glutamate receptor 2 – glutamate receptor 1 – gluR-K1 – OTTMUSP00000005878 – OTTMUSP00000005879 – glutamate receptor A – AMPA-selective glutamate receptor 1 – glutamate receptor ionotropic, AMPA 1 – gluR-K2 – glutamate receptor B – AMPA selective glutamate receptor – AMPA-selective glutamate receptor 2 – glutamate receptor ionotropic, AMPA 2 – glutamate receptor subunit GluR1 – glutamate receptor, ionotropic, AMPA1 (alpha 1)

Glutamate Receptor, Ionotrophic, AMPA 2/3 erfüllt eine Reihe von Funktionen:

extracellular-glutamate-gated ion channel activity – ion channel activity – kainate selective glutamate receptor activity – receptor activity – PDZ domain binding – alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity – protein binding – G-protein alpha-subunit binding – G-protein beta-subunit binding – adenylate cyclase binding – beta-2 adrenergic receptor binding – ionotropic glutamate receptor activity – myosin V binding – protein domain specific binding – protein kinase A binding – protein kinase binding – small GTPase binding – calcium channel regulator activity

Glutamate Receptor, Ionotrophic, AMPA 2/3 spielt in den folgenden Prozessen eine Rolle:

ion transport – signal transduction – synaptic transmission – establishment of protein localization – positive regulation of synaptic transmission – receptor internalization – regulation of receptor recycling – regulation of synaptic transmission, glutamatergic – response to lithium ion – long-term memory – positive regulation of membrane potential – regulation of action potential in neuron – regulation of synaptic plasticity – regulation of synaptic transmission – response to toxin – transport – ion transmembrane transport – response to fungicide

Glutamate Receptor, Ionotrophic, AMPA 2/3 ist wie folgt lokalisiert:

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex – cell junction – endocytic vesicle membrane – endoplasmic reticulum – integral to membrane – membrane fraction – plasma membrane – postsynaptic membrane – synapse – asymmetric synapse – cell soma – dendritic shaft – dendritic spine – growth cone – postsynaptic density – presynaptic membrane – protein complex – synaptic vesicle membrane – cytosol – early endosome – membrane – neuromuscular junction – neuron spine – neuronal cell body – synaptosome – dendrite – dendrite cytoplasm – perikaryon – terminal button – endoplasmic reticulum membrane – ionotropic glutamate receptor complex

Quelle: NCBI Entrez Gene, Gene Ontology