Die folgenden Gennamen und Gensymbole werden für Antigen Gap Junction Protein, alpha 1, 43kd über verschiedene Spezies hinweg verwendet:

gap junction protein, alpha 1, 43kDa (GJA1), gap junction protein, alpha 1 (Gja1), gap junction protein, beta 1 (Gjb1), connexin 43 (cx43), gap junction protein, alpha 1, 43kDa (gja1-A), gap junction protein, alpha 1, 43kDa (gja1), CONNEXIN 43 protein (CONNEXIN 43), connexin 43 (CX43)

Zu den weiteren Synonymen zählen:

CX43, GJAL, ODDD, DFNB38, Cx43, Npm1, Cnx43, Gja-1, AU042049, AW546267, Cx43alpha1, connexin43, Cx32, Cnx32, Gjb-1, MGC6217, AI118175, MGC93610, gja1, cx43a1, zfCx43.3, MGC128721, gja1-A, connexin 43, cx43, gjal, oddd, dfnb38, CONNEXIN 43

Auf Proteinebene tauchen folgende Bezeichner für Antigen Gap Junction Protein, alpha 1, 43kd auf:

connexin 43 – gap junction protein, alpha-like – gap junction 43 kDa heart protein – gap junction alpha-1 protein – connexin-43 – alpha 1 connexin – gap junction membrane channel protein alpha 1 – gap junction beta-1 protein – connexin 32 – connexin-32 – OTTMUSP00000019745 – OTTMUSP00000019746 – gap junction membrane channel protein beta 1 – gap junction protein, alpha 1 – shf – sof – etID309742.9 – short fin protein – cx43 – vascular smooth muscle connexin-43 – gap junction protein, alpha 1, 43 kD (connexin 43) – gap junction protein, alpha 1, 43kDa – alpha 1 gap junction protein – Gap junction alpha-1 protein – gap junction protein, alpha 1, 43kDa (connexin 43) – CONNEXIN 43 protein – Connexin-43 – gap junction protein alpha 1

Gap Junction Protein, alpha 1, 43kd erfüllt eine Reihe von Funktionen:

PDZ domain binding – SH3 domain binding – ion transmembrane transporter activity – protein binding – signal transducer activity – transmembrane transporter activity – gap junction channel activity – protein domain specific binding – receptor binding – gap junction hemi-channel activity – voltage-gated channel activity

Gap Junction Protein, alpha 1, 43kd spielt in den folgenden Prozessen eine Rolle:

ATP transport – apoptosis – cell-cell signaling – gap junction assembly – heart development – muscle contraction – negative regulation of cell proliferation – neuron projection morphogenesis – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of protein catabolic process – protein oligomerization – regulation of calcium ion transport – response to pH – vascular transport – adult heart development – blood vessel morphogenesis – cell communication – embryonic heart tube development – epithelial cell maturation – heart looping – in utero embryonic development – limb bud formation – negative regulation of gene expression – neuron migration – positive regulation of gene expression – positive regulation of striated muscle tissue development – regulation of heart contraction – skeletal muscle tissue regeneration – transmembrane transport – purine ribonucleotide transport – response to peptide hormone stimulus – caudal fin morphogenesis – cell differentiation – cell proliferation – embryonic hemopoiesis – embryonic skeletal joint morphogenesis – fin regeneration – multicellular organismal development

Gap Junction Protein, alpha 1, 43kd ist wie folgt lokalisiert:

Golgi apparatus – Golgi-associated vesicle membrane – cell junction – connexon complex – cytoplasm – early endosome – endoplasmic reticulum – fascia adherens – integral to plasma membrane – lysosome – membrane raft – mitochondrial outer membrane – multivesicular body – plasma membrane – cell-cell junction – cytosol – gap junction – integral to membrane – late endosome – membrane – endoplasmic reticulum membrane

Quelle: NCBI Entrez Gene, Gene Ontology