Die folgenden Gennamen und Gensymbole werden für Antigen Gap Junction Protein, alpha 1, 43kDa über verschiedene Spezies hinweg verwendet:

gap junction protein, alpha 1, 43kDa (GJA1), gap junction protein, alpha 1, 43kDa (gja1-A), gap junction protein, alpha 1, 43kDa (gja1)

Zu den weiteren Synonymen zählen:

CX43, GJAL, ODDD, DFNB38, MGC128721, gja1-A, connexin 43, cx43, gjal, oddd, dfnb38, connexin43, Cx43

Auf Proteinebene tauchen folgende Bezeichner für Antigen Gap Junction Protein, alpha 1, 43kDa auf:

connexin 43 – gap junction protein, alpha-like – gap junction 43 kDa heart protein – gap junction alpha-1 protein – cx43 – connexin-43 – vascular smooth muscle connexin-43 – gap junction protein, alpha 1, 43 kD (connexin 43) – gap junction protein, alpha 1, 43kDa – alpha 1 gap junction protein – gap junction protein, alpha 1, 43kDa (connexin 43) – Connexin-43 – Gap junction alpha-1 protein – gap junction protein alpha 1 – gap junction membrane channel protein alpha 1

Gap Junction Protein, alpha 1, 43kDa erfüllt eine Reihe von Funktionen:

PDZ domain binding – SH3 domain binding – ion transmembrane transporter activity – protein binding – signal transducer activity – transmembrane transporter activity – gap junction channel activity – receptor binding

Gap Junction Protein, alpha 1, 43kDa spielt in den folgenden Prozessen eine Rolle:

ATP transport – apoptosis – cell-cell signaling – gap junction assembly – heart development – muscle contraction – negative regulation of cell proliferation – neuron projection morphogenesis – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of protein catabolic process – protein oligomerization – regulation of calcium ion transport – response to pH – vascular transport – adult heart development – blood vessel morphogenesis – cell communication – embryonic heart tube development – epithelial cell maturation – heart looping – in utero embryonic development – limb bud formation – negative regulation of gene expression – neuron migration – positive regulation of gene expression – positive regulation of striated muscle tissue development – regulation of heart contraction – skeletal muscle tissue regeneration

Gap Junction Protein, alpha 1, 43kDa ist wie folgt lokalisiert:

Golgi apparatus – Golgi-associated vesicle membrane – cell junction – connexon complex – cytoplasm – early endosome – endoplasmic reticulum – fascia adherens – integral to plasma membrane – lysosome – membrane raft – mitochondrial outer membrane – multivesicular body – plasma membrane – cytosol – gap junction – integral to membrane – late endosome

Quelle: NCBI Entrez Gene, Gene Ontology