Die folgenden Gennamen und Gensymbole werden für Antigen Forkhead Box O4 über verschiedene Spezies hinweg verwendet:

forkhead box O4 (FOXO4), forkhead box O4 (Foxo4), similar to Putative fork head domain transcription factor AFX1 (Forkhead box protein O4) (FOXO4), forkhead box O4 (foxo4), forkhead box O4 (LOC100348179)

Zu den weiteren Synonymen zählen:

AFX, AFX1, MLLT7, MGC120490, afx, Afxh, Mllt7, MGC117660, RGD1561201, FOXO4, foxo4

Auf Proteinebene tauchen folgende Bezeichner für Antigen Forkhead Box O4 auf:

forkhead box O4 – myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 7 – myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7 – forkhead box protein O4 – forkhead protein – fork head domain transcription factor AFX1 – myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog – similar to Putative fork head domain transcription factor AFX1 (Forkhead box protein O4) – forkhead box protein O4-like – forkhead box O1A

Forkhead Box O4 erfüllt eine Reihe von Funktionen:

enzyme binding – sequence-specific DNA binding – transcription activator activity – transcription factor activity – transcription factor binding – DNA binding – sequence-specific DNA binding transcription factor activity – protein binding

Forkhead Box O4 spielt in den folgenden Prozessen eine Rolle:

G1 phase of mitotic cell cycle – cell cycle – cell cycle arrest – cell differentiation – insulin receptor signaling pathway – mitotic cell cycle G2/M transition DNA damage checkpoint – multicellular organismal development – muscle organ development – negative regulation of angiogenesis – negative regulation of cell proliferation – negative regulation of smooth muscle cell differentiation – positive regulation of transcription – regulation of transcription, DNA-dependent – transcription from RNA polymerase II promoter – regulation of transcription – transcription

Forkhead Box O4 ist wie folgt lokalisiert:

cytoplasm – cytosol – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology