Die folgenden Gennamen und Gensymbole werden für Antigen Forkhead Box A1 über verschiedene Spezies hinweg verwendet:

forkhead box A1 (FOXA1), forkhead box A1 (Foxa1), forkhead box A1 (foxa1), forkhead box A4 (foxa4), forkhead homolog (fkh), Me-FKH1 (foxa3), forkhead box A1 (LOC100301627)

Zu den weiteren Synonymen zählen:

HNF3A, TCF3A, MGC33105, Hnf3a, Tcf3a, Hnf-3a, Tcf-3a, fkd7, forkhead-7, foxa1, MGC52590, xfkh1, FoxA4a, MGC75967, pintallavis, tcf3a, xfkh2, tFoxA1, HNF3alpha, HNF3-alpha, fkh, FOXA1, Ci-fkh, HNF-3a, foxa3, Foxa1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Forkhead Box A1 auf:

forkhead box A1 – hepatocyte nuclear factor 3, alpha – hepatocyte nuclear factor 3-alpha – HNF-3-alpha – fork head domain – forkhead box protein A1 – hepatocyte nuclear factor 3 alpha (winged helix transcription factor) – HNF-3A – fork head domain protein 7 – forkhead box A4 – HNF3 alpha – HNF-3 alpha – forkhead transcription factor FoxA1 – forkhead homolog – hepatocyte nuclear factor 3 alpha – Me-FKH1 – hepatocyte nuclear factor 3-alpha-like

Forkhead Box A1 erfüllt eine Reihe von Funktionen:

sequence-specific DNA binding – transcription factor activity – DNA binding – double-stranded DNA binding – protein domain specific binding – sequence-specific DNA binding transcription factor activity – transcription activator activity – transcription factor binding – promoter binding

Forkhead Box A1 spielt in den folgenden Prozessen eine Rolle:

branching morphogenesis of a tube – epithelial cell differentiation – epithelial cell maturation – glucose homeostasis – hormone metabolic process – lung development – neuron fate specification – positive regulation of neuron differentiation – positive regulation of transcription from RNA polymerase II promoter – prostate gland development – regulation of transcription, DNA-dependent – chromatin modification – epithelial cell maturation involved in prostate gland development – epithelial tube branching involved in lung morphogenesis – epithelial-mesenchymal signaling involved in prostate gland development – lung epithelial cell differentiation – multicellular organismal development – negative regulation of transcription from RNA polymerase II promoter – prostate gland epithelium morphogenesis – prostate gland stromal morphogenesis – regulation of gene expression – regulation of transcription – secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development – transcription – tube morphogenesis – negative regulation of survival gene product expression – positive regulation of estrogen receptor signaling pathway – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of mitotic cell cycle – positive regulation of transcription factor activity – response to estradiol stimulus

Forkhead Box A1 ist wie folgt lokalisiert:

nucleus

Quelle: NCBI Entrez Gene, Gene Ontology