Die folgenden Gennamen und Gensymbole werden für Antigen Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) über verschiedene Spezies hinweg verwendet:

fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (flt1), fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1), FMS-like tyrosine kinase 1 (Flt1), fms-related tyrosine kinase 1 (Flt1), fms-related tyrosine kinase 1 (FLT1), vascular endothelial growth factor receptor 1 (CpipJ_CPIJ012087)

Zu den weiteren Synonymen zählen:

flt1b, VEGFR1, FLT, Flt-1, sFlt1, VEGFR-1, AI323757, FLT1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) auf:

fms-related tyrosine kinase 1 – FMS related tyrosine kinase 1 – receptor tyrosine kinase Flt1b – vascular endothelial growth factor/vascular permeability factor receptor – vascular endothelial growth factor receptor 1 – OTTMUSP00000023727 – embryonic receptor kinase 2 – tyrosine-protein kinase receptor FLT – vascular permeability factor receptor – vascular endothelial growth factor receptor-1 – FLT-1 – FMS-like tyrosine kinase 1 – Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) erfüllt eine Reihe von Funktionen:

ATP binding – kinase activity – nucleotide binding – protein binding – protein kinase activity – protein tyrosine kinase activity – receptor activity – transferase activity – transmembrane receptor protein tyrosine kinase activity – vascular endothelial growth factor receptor activity – growth factor binding – identical protein binding – receptor signaling protein tyrosine kinase activity

Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) spielt in den folgenden Prozessen eine Rolle:

protein amino acid phosphorylation – regulation of heart contraction – transmembrane receptor protein tyrosine kinase signaling pathway – vascular endothelial growth factor receptor signaling pathway – vasculogenesis – cell differentiation – cell migration – female pregnancy – multicellular organismal development – patterning of blood vessels – positive regulation of cell proliferation – positive regulation of vascular endothelial growth factor receptor signaling pathway – activation of MAPKK activity – angiogenesis – intracellular receptor mediated signaling pathway – peptidyl-tyrosine phosphorylation – phosphorylation – positive regulation of cell migration – positive regulation of fibroblast proliferation – positive regulation of smooth muscle cell proliferation – regulation of smooth muscle contraction – response to hypoxia – signal transduction – sprouting angiogenesis

Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) ist wie folgt lokalisiert:

integral to membrane – integral to plasma membrane – membrane – cytoplasm – extracellular region – extracellular space – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology