Die folgenden Gennamen und Gensymbole werden für Antigen Filamin A, alpha über verschiedene Spezies hinweg verwendet:

filamin A, alpha (FLNA), filamin, alpha (Flna), filamin A, alpha (actin binding protein 280) (flna), filamin B, like (flnbl), filamin A, alpha (flna), cheerio (cher)

Zu den weiteren Synonymen zählen:

FLN, FMD, MNS, OPD, ABPX, FLN1, NHBP, OPD1, OPD2, ABP-280, DKFZp434P031, Fln1, Dilp2, F730004A14Rik, FLNA, RGD1560614, fb98b06, wu:fb98b06, wu:fd09g03, wu:fd49a06, flna, cb967, wu:fd18g06, MGC147094, sko, DmelCG3937, CG3937

Auf Proteinebene tauchen folgende Bezeichner für Antigen Filamin A, alpha auf:

filamin A, alpha – filamin 1 – non-muscle filamin – actin binding protein 280 – endothelial actin-binding protein – filamin, alpha – GENA 379 – filamin A – dilated pupils 2 – actin-binding protein 280 – filamin A, alpha (actin binding protein 280) – fd09g03 – filamin-A – filamin B, like – cheerio, isoform A – CG3937-PA – cher-PA – cheerio – filamin B – filamin-240 – filamin – Filamin-A – shi kong – Filamin-1 – cheerio, isoform G – CG3937-PG – cher-PG – cheerio, isoform F – CG3937-PF – cher-PF – cheerio, isoform H – CG3937-PH – cher-PH – cheerio, isoform B – CG3937-PB – cher-PB

Filamin A, alpha erfüllt eine Reihe von Funktionen:

Fc-gamma receptor I complex binding – GTP-Ral binding – Rac GTPase binding – actin filament binding – glycoprotein binding – protein homodimerization activity – signal transducer activity – small GTPase binding – transcription factor binding – actin binding – protein binding – protein kinase C binding

Filamin A, alpha spielt in den folgenden Prozessen eine Rolle:

actin crosslink formation – actin cytoskeleton reorganization – cytoplasmic sequestering of protein – establishment of protein localization – inhibition of adenylate cyclase activity by dopamine receptor signaling pathway – negative regulation of protein catabolic process – negative regulation of transcription factor activity – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of transcription factor import into nucleus – protein localization at cell surface – protein stabilization – receptor clustering – early endosome to late endosome transport – biological_process – determination of adult lifespan – germarium-derived female germ-line cyst encapsulation – learning or memory – negative regulation of lamellocyte differentiation – olfactory learning – ovarian ring canal formation – protein localization – ring canal formation – ring canal formation, actin assembly

Filamin A, alpha ist wie folgt lokalisiert:

actin cytoskeleton – cell cortex – cytoplasm – cytosol – extracellular region – nucleus – plasma membrane – cytoskeleton – trans-Golgi network – cellular_component – germline ring canal inner rim – germline ring canal outer rim

Quelle: NCBI Entrez Gene, Gene Ontology