Die folgenden Gennamen und Gensymbole werden für Antigen Fibronectin 1 über verschiedene Spezies hinweg verwendet:

fibronectin 1 (FN1), fibronectin 1 (Fn1), fibronectin 1 (fn1)

Zu den weiteren Synonymen zählen:

FN, CIG, FNZ, MSF, ED-B, FINC, GFND, LETS, GFND2, DKFZp686H0342, DKFZp686I1370, DKFZp686F10164, DKFZp686O13149, Fn, Fn-1, MGC117493, E330027I09, fn-1, FIBNEC, FN1, cig, msf, finc, lets, MGC97508, fibronectin, fn2, fb80d10, wu:fb80d10

Auf Proteinebene tauchen folgende Bezeichner für Antigen Fibronectin 1 auf:

fibronectin 1 – OTTHUMP00000206762 – OTTHUMP00000206767 – cold-insoluble globulin – migration-stimulating factor – fibronectin – FN – fibronectin ED-A- region – fibronectin variable region – embryo-specific fibronectin 1 transcript – cumulus cell-specific fibronectin 1 transcript – gene C – nat – fn1l – natter – fibronectin-like

Fibronectin 1 erfüllt eine Reihe von Funktionen:

collagen binding – extracellular matrix structural constituent – heparin binding – mercury ion binding – peptidase activator activity – protease binding – protein binding – transferase activity, transferring acyl groups other than amino-acyl groups

Fibronectin 1 spielt in den folgenden Prozessen eine Rolle:

acute-phase response – cell adhesion – cell migration – peptide cross-linking – regulation of cell shape – response to wounding – substrate adhesion-dependent cell spreading – angiogenesis – anti-apoptosis – cell-matrix adhesion – cell-substrate junction assembly – extracellular matrix organization – positive regulation of peptidase activity – wound healing – ossification – metabolic process – cell-cell adhesion – embryonic heart tube development – establishment of epithelial cell apical/basal polarity – heart morphogenesis – somite specification – somitogenesis

Fibronectin 1 ist wie folgt lokalisiert:

ER-Golgi intermediate compartment – extracellular region – fibrinogen complex – platelet alpha granule lumen – proteinaceous extracellular matrix – apical plasma membrane – basement membrane – extracellular matrix – extracellular space

Quelle: NCBI Entrez Gene, Gene Ontology