Die folgenden Gennamen und Gensymbole werden für Antigen Fibroblast Growth Factor Receptor über verschiedene Spezies hinweg verwendet:

heartless (htl), fibroblast growth factor receptor (X1FGFR), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (Fgfr1), fibroblast growth factor receptor 1a (fgfr1a), Fibroblast growth factor receptor 1 (Fgfr1), fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor-1 (fgfr1-A), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 1 (MGC80912), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849)

Zu den weiteren Synonymen zählen:

CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, DFR1, DFR1/DFGF-R2, DPR3, DTRK(FR1), DmHD-38, Dtk1, EMS2, FGF-R2, FGFR, FGFR2, FR1, HD-38, HTL/FGFR1, Htl, Tk1, i100, i150, i79, j372, DmelCG7223, CG7223, X1FGFR, FGFR1, MGC83463, CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR, N-SAM, FLJ99988, Flt-2, Fgfr-1, AW208770, fgfr1, fgfr1-A, XFGFRA2, fgfr, FLG-1, cek, flg, flt2, kal2, bfgfr, cd331, fgfbr, flt-2, hbgfr, n-sam, xfgfr1, XFGFR-1, MGC80912

Auf Proteinebene tauchen folgende Bezeichner für Antigen Fibroblast Growth Factor Receptor auf:

heartless, isoform B – CG7223-PB – htl-PB – FGF receptor – fibroblast growth factor receptor – heartless – fibroblast growth factor receptor 1 – heartless, isoform A – CG7223-PA – htl-PA – heartless, isoform C – CG7223-PC – htl-PC – OTTHUMP00000190881 – soluble FGFR1 variant 1 – soluble FGFR1 variant 2 – FMS-like tyrosine kinase 2 – hydroxyaryl-protein kinase – fms-related tyrosine kinase 2 – heparin-binding growth factor receptor – basic fibroblast growth factor receptor 1 – MFR – c-fgr – bFGF-R-1 – OTTMUSP00000040525 – OTTMUSP00000040526 – OTTMUSP00000040527 – OTTMUSP00000040528 – OTTMUSP00000040529 – proto-oncogene c-Fgr – fibroblast growth factor receptor 1a – FGFR-1 – bFGF-R – FGF receptor-1 – fibroblast growth factor receptor-1 – cek1 protein – fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) – basic fibroblast growth factor receptor 1-like

Fibroblast Growth Factor Receptor erfüllt eine Reihe von Funktionen:

ATP binding – fibroblast growth factor receptor activity – protein tyrosine kinase activity – heparin binding – nucleotide binding – protein binding – receptor activity – transferase activity – cell adhesion molecule binding – fibroblast growth factor binding – glycoprotein binding – kinase activity – protein complex binding – protein kinase activity – transmembrane receptor protein tyrosine kinase activity

Fibroblast Growth Factor Receptor spielt in den folgenden Prozessen eine Rolle:

cardioblast differentiation – cell migration – central nervous system development – endoderm development – endodermal cell fate determination – fibroblast growth factor receptor signaling pathway – gastrulation – germ cell migration – glial cell migration – gonad development – gonadal mesoderm development – heart development – larval visceral muscle development – lymph gland development – mesoderm development – mesoderm migration – mesodermal cell fate commitment – mesodermal cell fate determination – mesodermal cell migration – muscle fiber development – muscle organ development – pericardial cell differentiation – pole cell migration – protein amino acid phosphorylation – regulation of cell shape – salivary gland development – somatic muscle development – ventral cord development – visceral muscle development – MAPKKK cascade – cell growth – skeletal system development – angiogenesis – blood vessel morphogenesis – brain development – branching involved in salivary gland morphogenesis – cell maturation – central nervous system neuron development – chondrocyte differentiation – embryonic limb morphogenesis – generation of neurons – in utero embryonic development – induction of an organ – inner ear morphogenesis – lung development – lung-associated mesenchyme development – mesenchymal cell differentiation – midbrain development – motogenic signaling involved in postnatal olfactory bulb interneuron migration – negative regulation of apoptosis – negative regulation of gene expression – negative regulation of osteoblast differentiation – neuron projection development – paraxial mesoderm development – phosphorylation – positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway – positive regulation of cardiac muscle cell proliferation – positive regulation of cell proliferation – positive regulation of mesenchymal cell proliferation – positive regulation of neuron projection development – regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling – regulation of cell proliferation – regulation of gene expression – regulation of lateral mesodermal cell fate specification – regulation of sensory perception of pain – regulation of stem cell proliferation – salivary gland morphogenesis – signal transduction – stem cell maintenance – ureteric bud development – anatomical structure homeostasis – cardiac muscle tissue development – dorsal/ventral pattern formation – fin regeneration – liver development – negative regulation of endodermal cell fate specification

Fibroblast Growth Factor Receptor ist wie folgt lokalisiert:

integral to membrane – plasma membrane – integral to plasma membrane – membrane fraction – membrane

Quelle: NCBI Entrez Gene, Gene Ontology