Die folgenden Gennamen und Gensymbole werden für Antigen Fibroblast Growth Factor 2 (Basic) über verschiedene Spezies hinweg verwendet:

fibroblast growth factor 2 (basic) (FGF2), fibroblast growth factor 2 (Fgf2), nudix (nucleoside diphosphate linked moiety X)-type motif 6 (nudt6), basic fibroblast growth factor (BFGF), fibroblast growth factor 2 (basic) (fgf2), fibroblast growth factor 2 (basic) (LOC100227798)

Zu den weiteren Synonymen zählen:

BFGF, FGFB, HBGF-2, bFGF, Fgf-2, FGF2, nudt6, fgf2, MGC52602, FGF-2, bfgf, fgfb, fgf-2, xfgf2, hbgh-2, HBGF2, LOC100227798, Fgfb

Auf Proteinebene tauchen folgende Bezeichner für Antigen Fibroblast Growth Factor 2 (Basic) auf:

fibroblast growth factor 2 – prostatropin – heparin-binding growth factor 2 – basic fibroblast growth factor bFGF – basic fibroblast growth factor – fibroblast growth factor 2 (basic) – nudix-type motif 6 – bFGF gene antisense transcript – Nucleoside diphosphate-linked moiety X motif 6 – basic fgf

Fibroblast Growth Factor 2 (Basic) erfüllt eine Reihe von Funktionen:

growth factor activity – heparin binding – protein binding – nerve growth factor receptor binding – voltage-gated calcium channel activity

Fibroblast Growth Factor 2 (Basic) spielt in den folgenden Prozessen eine Rolle:

Ras protein signal transduction – activation of MAPK activity – activation of MAPKK activity – apoptosis – cell migration involved in sprouting angiogenesis – chemotaxis – fibroblast growth factor receptor signaling pathway – glial cell differentiation – induction of an organ – lung development – multicellular organismal development – negative regulation of blood vessel endothelial cell migration – negative regulation of cell proliferation – nervous system development – organ morphogenesis – positive regulation of angiogenesis – positive regulation of blood vessel endothelial cell migration – positive regulation of cardiac muscle cell proliferation – positive regulation of cell differentiation – positive regulation of cell division – positive regulation of epithelial cell proliferation – positive regulation of granule cell precursor proliferation – positive regulation of protein amino acid phosphorylation – regulation of retinal cell programmed cell death – signal transduction – C21-steroid hormone biosynthetic process – angiogenesis – cell differentiation – negative regulation of cell growth – negative regulation of transcription, DNA-dependent – nuclear translocation of MAPK – positive regulation of cell proliferation – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – protein kinase cascade – regulation of calcium ion-dependent exocytosis – regulation of transcription, DNA-dependent – synaptic transmission – wound healing

Fibroblast Growth Factor 2 (Basic) ist wie folgt lokalisiert:

extracellular region – extracellular space – cytoplasm – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology