Die folgenden Gennamen und Gensymbole werden für Antigen Fas Ligand (TNF Superfamily, Member 6) über verschiedene Spezies hinweg verwendet:

Fas ligand (TNF superfamily, member 6) (FASLG), Fas ligand (TNF superfamily, member 6) (Fasl), Fas ligand (FASLG), Fas ligand (fasl), Fas (TNF receptor superfamily, member 6) (FAS), Fas (TNF receptor superfamily member 6) (Fas), Fas ligand (TNF superfamily, member 6) (Faslg), Fas (TNF receptor superfamily, member 6) (Fas), FAS antigen CD95 (LOC574159), Fas ligand (TNF superfamily, member 6) (faslg), Fas (TNF receptor superfamily, member 6) (fas)

Zu den weiteren Synonymen zählen:

FASL, CD178, CD95L, TNFSF6, APT1LG1, gld, Fas-L, Faslg, Tnfsf6, Fas-Ligand, FASLG, fasl, APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, lpr, APO1, TNFR6, Tnfrsf6, AI196731, Fasl, CD95-L, Apt1Lg1, FAS, LOC574159, zgc:162027

Auf Proteinebene tauchen folgende Bezeichner für Antigen Fas Ligand (TNF Superfamily, Member 6) auf:

fas ligand – CD95 ligand – apoptosis (APO-1) antigen ligand 1 – tumor necrosis factor (ligand) superfamily, member 6 – Fas ligand (TNF superfamily, member 6) – Fas antigen ligand – generalized lymphoproliferative disease – Fas ligand – APO-1 ligand – TNF superfamily, member 6 – tumor necrosis factor receptor superfamily, member 6 – Fas AMA – Fas antigen – CD95 antigen – apoptosis antigen 1 – APO-1 cell surface antigen – tumor necrosis factor receptor superfamily member 6 – apo-1 antigen – FASLG receptor – lymphoproliferation – Fas (TNF receptor superfamily member) – apoptosis-mediating surface antigen FAS – tumor necrosis factor ligand superfamily member 6 – CD95L protein – Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand) – Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand) – Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand) – Fas receptor – Fas antigen (ATP1) – Tumor necrosis factor receptor superfamily, member 6 – apoptosis (APO-1) antigen 1 ( FAS ), member 6 – Fas (TNF receptor superfamily, member 6) – fas antigen – fas ligand receptor soluble form – FAS antigen CD95 – Tumor necrosis factor ligand superfamily member 6 – Fas receptor CD95

Fas Ligand (TNF Superfamily, Member 6) erfüllt eine Reihe von Funktionen:

cytokine activity – tumor necrosis factor receptor binding – identical protein binding – kinase binding – transmembrane receptor activity – protein binding – receptor activity – tumor necrosis factor receptor activity – death receptor binding

Fas Ligand (TNF Superfamily, Member 6) spielt in den folgenden Prozessen eine Rolle:

activation of pro-apoptotic gene products – cell-cell signaling – immune response – induction of apoptosis by extracellular signals – necrotic cell death – positive regulation of I-kappaB kinase/NF-kappaB cascade – signal transduction – apoptosis – positive regulation of apoptosis – retinal cell programmed cell death – B cell mediated immunity – activation-induced cell death of T cells – anti-apoptosis – gene expression – immunoglobulin production – induction of apoptosis via death domain receptors – inflammatory cell apoptosis – negative regulation of B cell activation – negative thymic T cell selection – positive regulation of necrotic cell death – protein complex assembly – protein homooligomerization – regulation of lymphocyte differentiation – regulation of myeloid cell differentiation – renal system process – response to glucocorticoid stimulus – response to protein stimulus – response to toxin – spleen development – transformed cell apoptosis – T cell homeostasis – dendrite regeneration – negative regulation of apoptosis – regulation of cell proliferation – activation of caspase activity – cellular chloride ion homeostasis – cellular response to stress – endosomal lumen acidification – induction of necroptosis by extracellular signals – induction of necroptosis of activated-T cells – negative regulation of angiogenesis – positive regulation of cell proliferation – positive regulation of epidermal growth factor receptor signaling pathway – positive regulation of neuron apoptosis – response to growth factor stimulus – response to lipopolysaccharide – aging – induction of apoptosis – ovulation cycle – response to cytokine stimulus – response to drug – response to estrogen stimulus – response to hypoxia – response to inorganic substance – response to peptide hormone stimulus – spermatogenesis

Fas Ligand (TNF Superfamily, Member 6) ist wie folgt lokalisiert:

extracellular region – extracellular space – integral to plasma membrane – plasma membrane – external side of plasma membrane – integral to membrane – membrane – cytosol – death-inducing signaling complex – soluble fraction – cell surface – membrane raft – perinuclear region of cytoplasm – caveola – cytoplasmic membrane-bounded vesicle

Quelle: NCBI Entrez Gene, Gene Ontology