Die folgenden Gennamen und Gensymbole werden für Antigen Fas (TNF Receptor Superfamily, Member 6) über verschiedene Spezies hinweg verwendet:

Fas (TNF receptor superfamily, member 6) (FAS), Fas ligand (TNF superfamily, member 6) (FASLG), Fas (TNF receptor superfamily member 6) (Fas), Fas ligand (TNF superfamily, member 6) (Fasl), Fas ligand (TNF superfamily, member 6) (Faslg), Fas ligand (FASLG), FAS antigen CD95 (LOC574159), Fas ligand (TNF superfamily, member 6) (faslg), Fas ligand (fasl), Fas (TNF receptor superfamily, member 6) (Fas), Fas (TNF receptor superfamily, member 6) (fas)

Zu den weiteren Synonymen zählen:

APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, FASL, CD178, CD95L, TNFSF6, APT1LG1, lpr, APO1, TNFR6, Tnfrsf6, AI196731, gld, Fas-L, Faslg, Tnfsf6, Fas-Ligand, Fasl, CD95-L, Apt1Lg1, FASLG, LOC574159, fasl, zgc:162027, FAS

Auf Proteinebene tauchen folgende Bezeichner für Antigen Fas (TNF Receptor Superfamily, Member 6) auf:

tumor necrosis factor receptor superfamily, member 6 – Fas AMA – Fas antigen – CD95 antigen – apoptosis antigen 1 – APO-1 cell surface antigen – fas ligand – CD95 ligand – apoptosis (APO-1) antigen ligand 1 – tumor necrosis factor (ligand) superfamily, member 6 – tumor necrosis factor receptor superfamily member 6 – apo-1 antigen – FASLG receptor – lymphoproliferation – Fas (TNF receptor superfamily member) – apoptosis-mediating surface antigen FAS – Fas ligand (TNF superfamily, member 6) – Fas antigen ligand – generalized lymphoproliferative disease – tumor necrosis factor ligand superfamily member 6 – CD95L protein – Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand) – Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand) – Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand) – Fas (TNF receptor superfamily, member 6) – fas antigen – fas ligand receptor soluble form – Fas ligand – APO-1 ligand – TNF superfamily, member 6 – FAS antigen CD95 – Tumor necrosis factor ligand superfamily member 6 – Fas receptor – Fas antigen (ATP1) – Tumor necrosis factor receptor superfamily, member 6 – apoptosis (APO-1) antigen 1 ( FAS ), member 6 – Fas receptor CD95

Fas (TNF Receptor Superfamily, Member 6) erfüllt eine Reihe von Funktionen:

identical protein binding – kinase binding – transmembrane receptor activity – cytokine activity – tumor necrosis factor receptor binding – protein binding – receptor activity – tumor necrosis factor receptor activity – death receptor binding

Fas (TNF Receptor Superfamily, Member 6) spielt in den folgenden Prozessen eine Rolle:

B cell mediated immunity – activation of pro-apoptotic gene products – activation-induced cell death of T cells – anti-apoptosis – gene expression – immune response – immunoglobulin production – induction of apoptosis via death domain receptors – inflammatory cell apoptosis – negative regulation of B cell activation – negative thymic T cell selection – positive regulation of necrotic cell death – protein complex assembly – protein homooligomerization – regulation of lymphocyte differentiation – regulation of myeloid cell differentiation – renal system process – response to glucocorticoid stimulus – response to protein stimulus – response to toxin – signal transduction – spleen development – transformed cell apoptosis – cell-cell signaling – induction of apoptosis by extracellular signals – necrotic cell death – positive regulation of I-kappaB kinase/NF-kappaB cascade – T cell homeostasis – apoptosis – dendrite regeneration – negative regulation of apoptosis – positive regulation of apoptosis – regulation of cell proliferation – retinal cell programmed cell death – activation of caspase activity – cellular chloride ion homeostasis – cellular response to stress – endosomal lumen acidification – induction of necroptosis by extracellular signals – induction of necroptosis of activated-T cells – negative regulation of angiogenesis – positive regulation of cell proliferation – positive regulation of epidermal growth factor receptor signaling pathway – positive regulation of neuron apoptosis – response to growth factor stimulus – response to lipopolysaccharide – aging – induction of apoptosis – ovulation cycle – response to cytokine stimulus – response to drug – response to estrogen stimulus – response to hypoxia – response to inorganic substance – response to peptide hormone stimulus – spermatogenesis

Fas (TNF Receptor Superfamily, Member 6) ist wie folgt lokalisiert:

cytosol – death-inducing signaling complex – external side of plasma membrane – extracellular region – integral to membrane – plasma membrane – soluble fraction – extracellular space – integral to plasma membrane – cell surface – membrane – membrane raft – perinuclear region of cytoplasm – caveola – cytoplasmic membrane-bounded vesicle

Quelle: NCBI Entrez Gene, Gene Ontology