Die folgenden Gennamen und Gensymbole werden für Antigen Farnesyltransferase, CAAX Box, alpha über verschiedene Spezies hinweg verwendet:

farnesyltransferase, CAAX box, alpha (FNTA), farnesyltransferase, CAAX box, alpha (Fnta)

Zu den weiteren Synonymen zählen:

FPTA, PTAR2, PGGT1A, MGC99680, FTA, PFAS

Auf Proteinebene tauchen folgende Bezeichner für Antigen Farnesyltransferase, CAAX Box, alpha auf:

farnesyltransferase, CAAX box, alpha – FTase-alpha – GGTase-I-alpha – farnesyltransferase alpha-subunit – ras proteins prenyltransferase alpha – type I protein geranyl-geranyltransferase alpha subunit – protein prenyltransferase alpha subunit repeat containing 2 – protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha – CAAX farnesyltransferase subunit alpha – ras proteins prenyltransferase subunit alpha – type I protein geranyl-geranyltransferase subunit alpha – Farnesyltransferase, subunit alpha

Farnesyltransferase, CAAX Box, alpha erfüllt eine Reihe von Funktionen:

CAAX-protein geranylgeranyltransferase activity – acetylcholine receptor regulator activity – alpha-tubulin binding – microtubule binding – protein binding – protein farnesyltransferase activity – transferase activity – drug binding – isoprenoid binding – peptide binding – prenyltransferase activity – protein prenyltransferase activity – zinc ion binding

Farnesyltransferase, CAAX Box, alpha spielt in den folgenden Prozessen eine Rolle:

neurotransmitter receptor metabolic process – protein amino acid farnesylation – protein amino acid geranylgeranylation – transforming growth factor beta receptor signaling pathway – negative regulation of apoptosis – negative regulation of nitric-oxide synthase 2 biosynthetic process – positive regulation of cell cycle – positive regulation of cell proliferation – positive regulation of nitric-oxide synthase 2 biosynthetic process – protein amino acid prenylation – regulation of receptor activity – response to cytokine stimulus – response to inorganic substance – response to organic cyclic substance – response to protein stimulus – positive regulation of deacetylase activity – positive regulation of tubulin deacetylation

Farnesyltransferase, CAAX Box, alpha ist wie folgt lokalisiert:

cytoplasm – cytosol – microtubule associated complex – CAAX-protein geranylgeranyltransferase complex

Quelle: NCBI Entrez Gene, Gene Ontology