Die folgenden Gennamen und Gensymbole werden für Antigen Ecdysone Receptor über verschiedene Spezies hinweg verwendet:

Ecdysone receptor (EcR), ecdysone receptor (Ecr), ecdysone receptor (AaeL_AAEL009600), ecdysone receptor (CpipJ_CPIJ002963), ecdysone receptor (Bm1_29350), ecdysone receptor (Tsp_00867)

Zu den weiteren Synonymen zählen:

CG8347, DEcR, Dhr23, DmEcR, ECR, EcR-A, EcR-B, EcR-B1, EcRB-1, EcRB1, EcdR, NR1H1, anon-WO0229075.1, lie, ms(2)06410, ms(2)42A, snt, DmelCG1765, CG1765, EcRA, AmEcR, ECR-A, ECR-B, Ecr, NV11088

Auf Proteinebene tauchen folgende Bezeichner für Antigen Ecdysone Receptor auf:

ecdysone receptor, isoform A – CG1765-PA – EcR-PA – snaggletooth – long island expressway – male sterile(2)42A – ecdysone receptor – ecdysone receptor, isoform E – CG1765-PE – EcR-PE – ecdysone receptor, isoform D – CG1765-PD – EcR-PD – ecdysone receptor, isoform C – CG1765-PC – EcR-PC – ecdysone receptor, isoform B – CG1765-PB – EcR-PB – NR1H1 – ecdysteroid receptor – GLEAN_12112 – GLEAN_12113

Ecdysone Receptor erfüllt eine Reihe von Funktionen:

DNA binding – RNA polymerase I transcription factor activity – ecdysteroid hormone receptor activity – ligand-dependent nuclear receptor activity – protein binding – protein heterodimerization activity – sequence-specific DNA binding – steroid binding – transcription factor activity – zinc ion binding

Ecdysone Receptor spielt in den folgenden Prozessen eine Rolle:

autophagy – axonogenesis – border follicle cell migration – cardiac muscle tissue development – cardioblast differentiation – cell adhesion – chitin-based embryonic cuticle biosynthetic process – dendrite morphogenesis – determination of adult lifespan – dorsal vessel heart proper cell fate commitment – ecdysis, chitin-based cuticle – ecdysone receptor-mediated signaling pathway – ecdysone-mediated induction of salivary gland cell autophagic cell death – epidermis development – germ-band shortening – hatching – head involution – histoblast morphogenesis – imaginal disc eversion – imaginal disc-derived wing morphogenesis – larval central nervous system remodeling – larval wandering behavior – metamorphosis – muscle organ development – mushroom body development – negative regulation of transcription, DNA-dependent – neuron development – neuron remodeling – oogenesis – peripheral nervous system development – positive regulation of apoptosis – pupariation – regulation of development, heterochronic – regulation of rhodopsin gene expression – regulation of transcription from RNA polymerase II promoter – response to cocaine – sperm individualization – spermatid development

Ecdysone Receptor ist wie folgt lokalisiert:

cytoplasm – dendrite – ecdysone receptor holocomplex – nucleus – polytene chromosome

Quelle: NCBI Entrez Gene, Gene Ontology