Die folgenden Gennamen und Gensymbole werden für Antigen Deleted in Liver Cancer 1 über verschiedene Spezies hinweg verwendet:

deleted in liver cancer 1 (DLC1), deleted in liver cancer 1 (dlc1)

Zu den weiteren Synonymen zählen:

HP, ARHGAP7, STARD12, FLJ21120, p122-RhoGAP, rhogap7, MGC83845, MGC152430, Dlc-1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Deleted in Liver Cancer 1 auf:

deleted in liver cancer 1 – Rho-GTPase-activating protein 7 – START domain containing protein 12 – deleted in liver cancer 1 variant 2 – StAR-related lipid transfer protein 12 – StAR-related lipid transfer (START) domain containing 12 – Rho GTPase-activating protein 7 – rho GTPase-activating protein 7-like – rho GTPase-activating protein 7 – START domain-containing protein 12 – Rho-type GTPase-activating protein 7 – stAR-related lipid transfer protein 12 – Deleted in liver cancer 1 protein homolog

Deleted in Liver Cancer 1 erfüllt eine Reihe von Funktionen:

GTPase activator activity – Rac GTPase activator activity – SH2 domain binding – protein binding

Deleted in Liver Cancer 1 spielt in den folgenden Prozessen eine Rolle:

activation of caspase activity – focal adhesion formation – forebrain development – heart morphogenesis – hindbrain morphogenesis – induction of apoptosis – negative regulation of Rho protein signal transduction – negative regulation of cell migration – negative regulation of cell proliferation – negative regulation of stress fiber formation – neural tube closure – positive regulation of protein amino acid dephosphorylation – regulation of actin cytoskeleton organization – regulation of cell shape – signal transduction

Deleted in Liver Cancer 1 ist wie folgt lokalisiert:

caveola – cytoplasm – focal adhesion – intracellular – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology