Die folgenden Gennamen und Gensymbole werden für Antigen Dedicator of Cytokinesis 1 über verschiedene Spezies hinweg verwendet:

dedicator of cytokinesis 1 (DOCK1), dedicator of cytokinesis 1 (Dock1), dedicator of cytokinesis 1 (dock1), dedicator of cytokinesis protein 1 (CpipJ_CPIJ002759), dedicator of cytokinesis 11 (Dock11), dedicator of cytokinesis 11 (DOCK11), Dedicator of cytokinesis protein 11 (doc11), dedicator of cytokinesis 11 (dock11)

Zu den weiteren Synonymen zählen:

ced5, DOCK180, AI854900, 9130006G06Rik, D630004B07Rik, DOCK1, sph238, Zizimin2, 8030476J24, 5033414A21Rik, ACG, ZIZ2, FLJ32122, FLJ43653, bB128O4.1, MGC140073

Auf Proteinebene tauchen folgende Bezeichner für Antigen Dedicator of Cytokinesis 1 auf:

dedicator of cytokinesis 1 – dedicator of cyto-kinesis 1 – dedicator of cytokinesis protein 1 – DOCK180 – 180 kDa protein downstream of CRK – dedicator of cytokinesis protein 1-like – dedicator of cytokinesis protein 11 – ACG – zizimin-2 – OTTMUSP00000018699 – OTTMUSP00000018704 – spleen specific 238 kDa protein with PH domain – activated Cdc42-associated guanine nucleotide exchange factor – dedicator of cytokinesis 11 – zizimin2 – bB128O4.1.1 (novel protein) – Activated Cdc42-associated guanine nucleotide exchange factor, ACG – Dedicator of cytokinesis protein 11 – dedicator of cytokinesis protein 11-like

Dedicator of Cytokinesis 1 erfüllt eine Reihe von Funktionen:

GTPase activator activity – SH3 domain binding – guanyl-nucleotide exchange factor activity – protein binding – GTP binding – GTPase binding – Rho GTPase binding – Rho guanyl-nucleotide exchange factor activity

Dedicator of Cytokinesis 1 spielt in den folgenden Prozessen eine Rolle:

apoptosis – integrin-mediated signaling pathway – phagocytosis, engulfment – signal transduction – small GTPase mediated signal transduction – cell migration – phagocytosis – myoblast fusion – regulation of catalytic activity

Dedicator of Cytokinesis 1 ist wie folgt lokalisiert:

cytoplasm – membrane – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology