Die folgenden Gennamen und Gensymbole werden für Antigen Cystatin C über verschiedene Spezies hinweg verwendet:

cystatin C (CST3), cystatin C (Cst3), cystatin C (LOC574313), cystatin C (cst3), cystatin C (amyloid angiopathy and cerebral hemorrhage) (cst3), cystatin C (LOC100009450), hypothetical protein (cystatin 3)

Zu den weiteren Synonymen zählen:

ARMD11, MGC117328, CysC, CYSC, MGC105556, CST3, MGC133662, LOC574313, armd11, fb51d07, MGC136227, MGC192989, wu:fb24g06, wu:fb51d07, wu:fc55f03, zgc:136227, LOC100009450

Auf Proteinebene tauchen folgende Bezeichner für Antigen Cystatin C auf:

cystatin C – cystatin 3 – gamma-trace – OTTHUMP00000164181 – OTTHUMP00000164182 – post-gamma-globulin – bA218C14.4 (cystatin C) – neuroendocrine basic polypeptide – OTTMUSP00000016736 – cystatin-C – cystatin-3 – Cystatin C (cysteine proteinase inhibitor) – cystatin C (amyloid angiopathy and cerebral hemorrhage) – hypothetical protein

Cystatin C erfüllt eine Reihe von Funktionen:

beta-amyloid binding – cysteine-type endopeptidase inhibitor activity – peptidase inhibitor activity – protease binding – protein binding

Cystatin C spielt in den folgenden Prozessen eine Rolle:

defense response – fibril organization – negative regulation of blood vessel remodeling – negative regulation of collagen catabolic process – negative regulation of elastin catabolic process – negative regulation of extracellular matrix disassembly – negative regulation of histolysis – negative regulation of peptidase activity – regulation of tissue remodeling – extracellular region – Sertoli cell development – apoptosis – brain development – cell activation – cellular response to hydrogen peroxide – cellular response to oxidative stress – circadian sleep/wake cycle, REM sleep – embryo implantation – eye development – male gonad development – negative regulation of cell death – positive regulation of DNA replication – positive regulation of cell proliferation – regulation of programmed cell death – response to axon injury – response to carbohydrate stimulus – response to drug – response to estradiol stimulus – response to hypoxia – response to inorganic substance – response to nutrient levels – response to organic cyclic substance – response to oxidative stress – response to protein stimulus – response to stimulus – response to toxin – salivary gland development – biological_process

Cystatin C ist wie folgt lokalisiert:

extracellular region – extracellular space – axon part – basement membrane – cell projection – contractile fiber – cytoplasm – endoplasmic reticulum – lysosome – multivesicular body – neuronal cell body – nuclear membrane – perinuclear region of cytoplasm – vesicle – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology