Die folgenden Gennamen und Gensymbole werden für Antigen Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) über verschiedene Spezies hinweg verwendet:

cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 (PSMD9), cyclin-dependent kinase inhibitor 1B (Cdkn1b), cyclin-dependent kinase inhibitor 1b (p27, kip1) (cdkn1b)

Zu den weiteren Synonymen zählen:

KIP1, MEN4, CDKN4, MEN1B, P27KIP1, p27, Rpn4, MGC8644, Kip1, Cdki1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03, CDKN1B

Auf Proteinebene tauchen folgende Bezeichner für Antigen Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) auf:

cyclin-dependent kinase inhibitor 1B – proteasome 26S non-ATPase subunit 9 – homolog of rat Bridge 1 – 26S proteasome regulatory subunit p27 – proteasome 26S non-ATPase regulatory subunit 9 – cyclin-dependent kinase inhibitor 1B (p27, kip1) – cyclin-dependent kinase inhibitor p27 – cyclin-dependent kinase inhibitor p27/Kip1 – Cyclin-dependent kinase inhibitor 1B (p27 Kip1) – Cyclin-dependent kinase inhibitor 1B (p27, Kip1) – cyclin-dependent kinase inhibitor 1b (p27, kip1) – fb64g10 – cyclin-dependent kinase inhibitor 1B (p27, Kip1) – p27Kip1

Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) erfüllt eine Reihe von Funktionen:

cyclin-dependent protein kinase inhibitor activity – protein binding – protein kinase inhibitor activity – transforming growth factor beta receptor, cytoplasmic mediator activity – bHLH transcription factor binding – transcription coactivator activity – Hsp70 protein binding – chaperone binding – protein complex binding – kinase activity

Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) spielt in den folgenden Prozessen eine Rolle:

G1/S transition of mitotic cell cycle – autophagic cell death – cell cycle – cell cycle arrest – induction of apoptosis – negative regulation of cell growth – negative regulation of cell proliferation – negative regulation of gene-specific transcription – negative regulation of kinase activity – negative regulation of phosphorylation – regulation of cyclin-dependent protein kinase activity – anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process – negative regulation of insulin secretion – negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle – positive regulation of insulin secretion – positive regulation of transcription – positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle – ubiquitin-dependent protein catabolic process – cell death – response to amino acid stimulus – response to cadmium ion – response to drug – response to estradiol stimulus – response to glucose stimulus – response to hypoxia – response to organic cyclic substance – response to peptide hormone stimulus – response to stress – inner ear development – negative regulation of cell motion – negative regulation of cyclin-dependent protein kinase activity – negative regulation of epithelial cell proliferation – positive regulation of cell proliferation – positive regulation of microtubule polymerization – potassium ion transport – sensory perception of sound

Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) ist wie folgt lokalisiert:

cytoplasm – cytosol – nucleus – proteasome complex – proteasome regulatory particle – protein complex

Quelle: NCBI Entrez Gene, Gene Ontology