Die folgenden Gennamen und Gensymbole werden für Antigen Crystallin, alpha B über verschiedene Spezies hinweg verwendet:

crystallin, alpha B (CRYAB), crystallin, alpha B (Cryab), hypothetical protein (alpha-B-crystallin), alpha-crystallin B chain-like (LOC100519789)

Zu den weiteren Synonymen zählen:

CRYA2, CTPP2, HSPB5, Crya2, HspB5, Crya-2, AACRYA, CRYAB, DKFZp468D2015, Cryab

Auf Proteinebene tauchen folgende Bezeichner für Antigen Crystallin, alpha B auf:

crystallin, alpha B – alpha B crystallin – alpha crystallin B chain – heat-shock 20 kD like-protein – alpha B-crystallin – crystallin, alpha 2 – Crystallin, alpha polypeptide 2 – alpha-crystallin B chain – alpha(B)-crystallin – crystallin, alpha polypeptide 2 – alpha-B-crystallin – Alpha-crystallin B chain – alphaB-crystallin – hypothetical protein – alpha-crystallin B chain-like – Alpha(B)-crystallin

Crystallin, alpha B erfüllt eine Reihe von Funktionen:

structural constituent of eye lens – unfolded protein binding – cytoskeletal protein binding – microtubule binding – protein homodimerization activity – protein binding

Crystallin, alpha B spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – camera-type eye development – muscle contraction – muscle organ development – negative regulation of intracellular transport – protein folding – protein homooligomerization – response to heat – aging – glucose metabolic process – microtubule polymerization or depolymerization – negative regulation of apoptosis – negative regulation of cell growth – oxygen and reactive oxygen species metabolic process – response to estradiol stimulus – response to hydrogen peroxide – response to stress – stress-activated MAPK cascade – apoptosis involved in morphogenesis – lens development in camera-type eye – negative regulation of caspase activity – negative regulation of gene expression – response to hypoxia – tubulin complex assembly

Crystallin, alpha B ist wie folgt lokalisiert:

Z disc – contractile fiber – cytoplasm – insoluble fraction – plasma membrane – soluble fraction – Golgi apparatus – actin filament bundle – cell surface – microtubule cytoskeleton – cytosol – mitochondrion

Quelle: NCBI Entrez Gene, Gene Ontology