Die folgenden Gennamen und Gensymbole werden für Antigen Coagulation Factor II (thrombin) über verschiedene Spezies hinweg verwendet:

coagulation factor II (thrombin) (F2), coagulation factor II (F2), coagulation factor II (thrombin) (f2)

Zu den weiteren Synonymen zählen:

PT, Cf2, FII, Cf-2, thrombin, F2, zgc:66319, wu:fb57c10, wu:fd42e09, wu:fd59d01, DKFZp470K2111, DKFZp470L0512

Auf Proteinebene tauchen folgende Bezeichner für Antigen Coagulation Factor II (thrombin) auf:

coagulation factor II – serine protease – prothrombin B-chain – prothrombin – OTTMUSP00000015068 – coagulation factor 2 – thrombin

Coagulation Factor II (thrombin) erfüllt eine Reihe von Funktionen:

calcium ion binding – peptidase activity – receptor binding – serine-type endopeptidase activity – thrombospondin receptor activity – catalytic activity – hydrolase activity – protein binding – serine-type peptidase activity

Coagulation Factor II (thrombin) spielt in den folgenden Prozessen eine Rolle:

STAT protein nuclear translocation – activation of caspase activity – acute-phase response – cell surface receptor linked signal transduction – cytosolic calcium ion homeostasis – fibrinolysis – multicellular organismal development – platelet activation – positive regulation of blood coagulation – positive regulation of collagen biosynthetic process – positive regulation of protein amino acid phosphorylation – positive regulation of release of sequestered calcium ion into cytosol – proteolysis – response to wounding – tyrosine phosphorylation of STAT protein – blood coagulation – metabolic process – positive regulation of cell growth – positive regulation of cell proliferation – positive regulation of phosphoinositide 3-kinase cascade – regulation of cell shape – thrombin receptor signaling pathway – cell surface receptor linked signaling pathway – negative regulation of astrocyte differentiation – negative regulation of proteolysis – response to stress – wound healing

Coagulation Factor II (thrombin) ist wie folgt lokalisiert:

extracellular region – extracellular space – plasma membrane – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology