Die folgenden Gennamen und Gensymbole werden für Antigen Clusterin über verschiedene Spezies hinweg verwendet:

clusterin (Clu), clusterin (CLU), clusterin-1 (LOC100136120), clusterin (clu), clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (clu), clusterin (LOC100034172), Clusterin (clus)

Zu den weiteren Synonymen zählen:

Cli, ApoJ, Sgp2, SP-40, Sgp-2, Sugp-2, AI893575, D14Ucla3, CLU, LOC100136120, CLI, AAG4, APOJ, KUB1, SGP2, SGP-2, TRPM2, TRPM-2, MGC24903, DAG, SP40, Trpm2, Trpmb, TRPM2B, RATTRPM2B, gpIII, clu, MGC53055, MGC73352, zgc:73352, GP80, xclu, MGC89163, LOC100034172

Auf Proteinebene tauchen folgende Bezeichner für Antigen Clusterin auf:

clusterin – Apolipoprotein J – complement lysis inhibitor – testosterone repressed prostate message – testosterone repressed prostate message-2 – complement cytolysis inhibitor – clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) – apolipoprotein J/clusterin – clusterin-1 – apolipoprotein J – sulfated glycoprotein 2 – aging-associated protein 4 – complement-associated protein SP-40 – testosterone-repressed prostate message 2 – dimeric acid glycoprotein – testosterone-repressed prostate message – testostrone-repressed prostate message 2 – testosterone repressed prostate message 2 – glycoprotein III – glycoprotein 80 – Clusterin

Clusterin erfüllt eine Reihe von Funktionen:

cell death – low-density lipoprotein receptor binding – protein binding – misfolded protein binding

Clusterin spielt in den folgenden Prozessen eine Rolle:

extracellular region – cell death – ovarian follicle atresia – ovarian follicle development – anti-apoptosis – complement activation, classical pathway – endocrine pancreas development – innate immune response – lipid metabolic process – negative regulation of protein homooligomerization – neuron projection morphogenesis – positive regulation of cell differentiation – positive regulation of cell proliferation – release of cytochrome c from mitochondria – response to oxidative stress – reverse cholesterol transport – apoptosis – multicellular organismal development – negative regulation of apoptosis – response to misfolded protein – response to stress – response to virus – response to wounding – spermatogenesis

Clusterin ist wie folgt lokalisiert:

nucleus – aggresome – extracellular region – extracellular space – mitochondrion – perinuclear region of cytoplasm – platelet alpha granule lumen – spherical high-density lipoprotein particle – extracellular matrix – chromaffin granule – cytoplasmic vesicle

Quelle: NCBI Entrez Gene, Gene Ontology