Die folgenden Gennamen und Gensymbole werden für Antigen Class II, Major Histocompatibility Complex, Transactivator über verschiedene Spezies hinweg verwendet:

class II, major histocompatibility complex, transactivator (CIITA), class II transactivator (Ciita), class II, major histocompatibility complex, transactivator (ciita)

Zu den weiteren Synonymen zählen:

C2TA, NLRA, MHC2TA, CIITAIV, C2ta, Mhc2ta, CIITA

Auf Proteinebene tauchen folgende Bezeichner für Antigen Class II, Major Histocompatibility Complex, Transactivator auf:

class II transactivator – NLR family, acid domain containing – MHC class II transactivator type III – nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing – MHC class II transactivator – MHC class II transactivator type IV – class II, major histocompatibility complex, transactivator – class II transactivator-like – MHC class II transactivator-like

Class II, Major Histocompatibility Complex, Transactivator erfüllt eine Reihe von Funktionen:

ATP binding – DNA binding – RNA polymerase II transcription factor activity – nucleotide binding – promoter binding – protein C-terminus binding – protein complex binding – transcription activator binding – transcription coactivator activity – transcription repressor activity – ubiquitin binding – protein binding – transcription activator activity – transcription regulator activity

Class II, Major Histocompatibility Complex, Transactivator spielt in den folgenden Prozessen eine Rolle:

immune response – negative regulation of collagen biosynthetic process – negative regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of MHC class II biosynthetic process – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription – response to antibiotic – response to interferon-gamma – inflammatory response – negative regulation of transcription – negative regulation of transcription, DNA-dependent – positive regulation of transcription, DNA-dependent

Class II, Major Histocompatibility Complex, Transactivator ist wie folgt lokalisiert:

nucleus

Quelle: NCBI Entrez Gene, Gene Ontology