Die folgenden Gennamen und Gensymbole werden für Antigen Ciliary Neurotrophic Factor über verschiedene Spezies hinweg verwendet:

zinc finger protein 91 homolog (mouse) (ZFP91), ciliary neurotrophic factor (CNTF), ciliary neurotrophic factor (Cntf)

Zu den weiteren Synonymen zählen:

ZFP91, CNTF, GPA, HCNTF, AI429687, MGC41235

Auf Proteinebene tauchen folgende Bezeichner für Antigen Ciliary Neurotrophic Factor auf:

zinc finger protein 91 homolog (mouse) – ciliary neurotrophic factor – growth-promoting activity factor – ciliary neurotropic factor – OTTMUSP00000029848

Ciliary Neurotrophic Factor erfüllt eine Reihe von Funktionen:

zinc ion binding – growth factor activity – ciliary neurotrophic factor receptor binding – interleukin-6 receptor binding – protein binding – cytokine activity

Ciliary Neurotrophic Factor spielt in den folgenden Prozessen eine Rolle:

growth – cell differentiation – multicellular organismal development – muscle organ morphogenesis – negative regulation of photoreceptor cell differentiation – nervous system development – neuron development – positive regulation of cell proliferation – positive regulation of tyrosine phosphorylation of Stat3 protein – regulation of retinal cell programmed cell death – ciliary neurotrophic factor-mediated signaling pathway – signal transduction – JAK-STAT cascade – astrocyte activation – membrane hyperpolarization – negative regulation of neuron apoptosis – neuroprotection – positive regulation of JAK-STAT cascade – positive regulation of MAPKKK cascade – positive regulation of axon regeneration – positive regulation of cell growth – positive regulation of hormone secretion – positive regulation of phosphoinositide 3-kinase cascade – protein heterooligomerization – regulation of resting membrane potential

Ciliary Neurotrophic Factor ist wie folgt lokalisiert:

cytoplasm – intracellular – extracellular space – axon – cell projection cytoplasm – cytosol – neuronal cell body – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology