Die folgenden Gennamen und Gensymbole werden für Antigen Chemokine Receptor 4 über verschiedene Spezies hinweg verwendet:

chemokine (C-X-C motif) receptor 4 (Cxcr4), chemokine receptor 4 (cxcr4)

Zu den weiteren Synonymen zählen:

CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, PBSF/SDF-1, cxcr4, xCXCR4, cxcr4-A, CXC-R4-A, CXCR-4-A, MGC82907

Auf Proteinebene tauchen folgende Bezeichner für Antigen Chemokine Receptor 4 auf:

C-X-C chemokine receptor type 4 – fusin – CXC-R4 – CXCR-4 – SDF-1 receptor – OTTMUSP00000022912 – OTTMUSP00000022913 – chemokine receptor 4 – chemokine (C-X-C) receptor 4 – pre-B-cell-derived chemokine receptor – stromal cell-derived factor 1 receptor – leukocyte-expressed seven-transmembrane-domain – leukocyte-derived seven transmembrane domain receptor – SDF-1 receptor-A – C-X-C chemokine receptor type 4-A – Stromal cell-derived factor 1 receptor-A

Chemokine Receptor 4 erfüllt eine Reihe von Funktionen:

C-C chemokine receptor activity – C-X-C chemokine receptor activity – G-protein coupled receptor activity – protein binding – receptor activity – signal transducer activity

Chemokine Receptor 4 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – T cell proliferation – ameboidal cell migration – brain development – cardiac muscle contraction – cell migration – epithelial cell development – germ cell development – germ cell migration – motor axon guidance – nervous system development – neuron migration – organ morphogenesis – patterning of blood vessels – regulation of calcium ion transport – regulation of cell migration – regulation of chemotaxis – regulation of programmed cell death – signal transduction – telencephalon cell migration

Chemokine Receptor 4 ist wie folgt lokalisiert:

endosome – growth cone – integral to membrane – membrane – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology