Die folgenden Gennamen und Gensymbole werden für Antigen Chemokine (C-X-C Motif) Receptor 4 über verschiedene Spezies hinweg verwendet:

chemokine (C-X-C motif) receptor 4 (CXCR4), chemokine (C-X-C motif) receptor 4 (Cxcr4), chemokine (C-X-C motif) receptor 4 (cxcr4)

Zu den weiteren Synonymen zählen:

FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E, Sdf1r, Cmkar4, PB-CKR, PBSF/SDF-1, MGC108696, CXCR4, MGC128682, cxcr4, cxcr4-B, CXC-R4-B, CXCR-4-B, MGC52882, MGC130802, fb22, hm89, lap3, lcr1, npyr, whim, cd184, lestr, npy3r, npyrl, CXC-R4, CXCR-4, hsy3rr, npyy3r, xcxcr4, d2s201e

Auf Proteinebene tauchen folgende Bezeichner für Antigen Chemokine (C-X-C Motif) Receptor 4 auf:

chemokine (C-X-C motif) receptor 4 – fusin – CD184 antigen – neuropeptide Y receptor Y3 – C-X-C chemokine receptor type 4 – seven transmembrane helix receptor – stromal cell-derived factor 1 receptor – lipopolysaccharide-associated protein 3 – seven-transmembrane-segment receptor, spleen – leukocyte-derived seven-transmembrane-domain receptor – CXC-R4 – CXCR-4 – SDF-1 receptor – OTTMUSP00000022912 – OTTMUSP00000022913 – chemokine receptor 4 – chemokine (C-X-C) receptor 4 – pre-B-cell-derived chemokine receptor – leukocyte-expressed seven-transmembrane-domain – leukocyte-derived seven transmembrane domain receptor – LESTR – CXC chemokine receptor – chemokine receptor (LCR1) – SDF-1 receptor-B – C-X-C chemokine receptor type 4-B – Stromal cell-derived factor 1 receptor-B – chemokine receptor CXCR4 – CXC chemokine receptor 4 – Stromal cell-derived factor 1 receptor

Chemokine (C-X-C Motif) Receptor 4 erfüllt eine Reihe von Funktionen:

C-C chemokine receptor activity – C-X-C chemokine receptor activity – G-protein coupled receptor activity – actin binding – coreceptor activity – myosin light chain binding – protein binding – receptor activity – signal transducer activity – ubiquitin binding – ubiquitin protein ligase binding

Chemokine (C-X-C Motif) Receptor 4 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – activation of MAPK activity – apoptosis – chemotaxis – elevation of cytosolic calcium ion concentration – immune response – inflammatory response – initiation of viral infection – interspecies interaction between organisms – response to hypoxia – response to virus – signal transduction – T cell proliferation – ameboidal cell migration – brain development – cardiac muscle contraction – cell migration – epithelial cell development – germ cell development – germ cell migration – motor axon guidance – nervous system development – neuron migration – organ morphogenesis – patterning of blood vessels – regulation of calcium ion transport – regulation of cell migration – regulation of chemotaxis – regulation of programmed cell death – telencephalon cell migration – neuron recognition

Chemokine (C-X-C Motif) Receptor 4 ist wie folgt lokalisiert:

cell leading edge – cytoplasm – integral to plasma membrane – plasma membrane – endosome – growth cone – integral to membrane – membrane – cell surface – cytoplasmic membrane-bounded vesicle – cytoplasmic vesicle

Quelle: NCBI Entrez Gene, Gene Ontology