Die folgenden Gennamen und Gensymbole werden für Antigen Chemokine (C-X-C Motif) Receptor 2 über verschiedene Spezies hinweg verwendet:

interleukin 8 receptor, beta (IL8RB), chemokine (C-X-C motif) receptor 2 (Cxcr2), interleukin 8 receptor, beta (Il8rb), chemokine (C-X-C motif) receptor 2 (CXCR2)

Zu den weiteren Synonymen zählen:

CD182, CXCR2, IL8R2, IL8RA, CMKAR2, CDw128b, CD128, Il8rb, CDw128, Cmkar2, Gpcr16, IL-8Rh, IL-8rb, mIL-8RH, Cxcr2, IL8RB

Auf Proteinebene tauchen folgende Bezeichner für Antigen Chemokine (C-X-C Motif) Receptor 2 auf:

interleukin 8 receptor beta – GRO/MGSA receptor – interleukin 8 receptor B – chemokine (CXC) receptor 2 – interleukin 8 receptor type 2 – interleukin-8 receptor type B – CXCR2 gene for IL8 receptor type B – chemokine (C-X-C motif) receptor 2 – high affinity interleukin-8 receptor B – C-X-C chemokine receptor type 2 – CXC-R2 – CXCR-2 – IL-8R B – IL-8 receptor alpha chain – chemokine (C-X-C) receptor 2 – interleukin 8 receptor, beta – interleukin-8 receptor CXCR2 – interleukin 8 receptor, alpha – interleukin-8 receptor, beta – chemokine receptor CXCR2 – IL-8 receptor

Chemokine (C-X-C Motif) Receptor 2 erfüllt eine Reihe von Funktionen:

G-protein coupled receptor activity – interleukin-8 receptor activity – protein binding – receptor activity – chemokine receptor activity – signal transducer activity – C-X-C chemokine receptor activity – interleukin-8 binding

Chemokine (C-X-C Motif) Receptor 2 spielt in den folgenden Prozessen eine Rolle:

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger – apoptosis – cellular defense response – chemotaxis – inflammatory response – neutrophil activation – neutrophil chemotaxis – positive regulation of cell proliferation – G-protein coupled receptor protein signaling pathway – cytokine-mediated signaling pathway – signal transduction – cell surface receptor linked signaling pathway

Chemokine (C-X-C Motif) Receptor 2 ist wie folgt lokalisiert:

cell surface – integral to plasma membrane – intracellular – mast cell granule – plasma membrane – integral to membrane – membrane

Quelle: NCBI Entrez Gene, Gene Ontology