Die folgenden Gennamen und Gensymbole werden für Antigen Chemokine (C-X-C Motif) Ligand 12 über verschiedene Spezies hinweg verwendet:

chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) (CXCL12), CXCL12 (LOC100304642), chemokine (C-X-C motif) ligand 12 (Cxcl12), chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) (Cxcl12), stromal cell-derived factor 1a (sdf1a), stromal cell-derived factor 1a (a-sdf1a)

Zu den weiteren Synonymen zählen:

CXCL12, DKFZp469G1525, PBSF, SDF1, SDF1A, SDF1B, TPAR1, SCYB12, SDF-1a, SDF-1b, TLSF-a, TLSF-b, Pbsf, Sdf1, Tlsf, Sdf1a, Sdf1b, Tlsfa, Tlsfb, Tpar1, Scyb12, AI174028, sdf1a, a-sdf1a

Auf Proteinebene tauchen folgende Bezeichner für Antigen Chemokine (C-X-C Motif) Ligand 12 auf:

chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) – chemokine CXCL12/SDF-1ALPHA – CXCL12 – stromal cell-derived factor 1a – stromal cell-derived factor 1 delta – stromal cell-derived factor 1 gamma – stromal cell-derived factor 1 – OTTMUSP00000026112 – OTTMUSP00000026113 – OTTMUSP00000026114 – C-X-C motif chemokine 12 – pre-B cell growth-stimulating factor – pre-B-cell growth-stimulating factor – thymic lymphoma cell-stimulating factor – 12-O-tetradecanoylphorbol 13-acetate repressed protein 1 – chemokine (C-X-C motif) ligand 12 – SDF-1 gamma – Stromal cell-derived factor 1 – stromal cell-derived factor-1 gamma

Chemokine (C-X-C Motif) Ligand 12 erfüllt eine Reihe von Funktionen:

chemokine activity – growth factor activity – signal transducer activity – cytokine activity

Chemokine (C-X-C Motif) Ligand 12 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – blood circulation – cell adhesion – cellular calcium ion homeostasis – chemotaxis – immune response – regulation of actin polymerization or depolymerization – response to virus – signal transduction – T cell proliferation – adult locomotory behavior – ameboidal cell migration – brain development – germ cell development – germ cell migration – induction of positive chemotaxis – motor axon guidance – neuron migration – organ regeneration – patterning of blood vessels – positive regulation of axon extension involved in axon guidance – positive regulation of calcium ion transport via voltage-gated calcium channel activity – positive regulation of cell migration – positive regulation of cell proliferation – positive regulation of dopamine secretion – positive regulation of endothelial cell proliferation – positive regulation of neuron differentiation – regulation of cell migration – telencephalon cell migration – cell migration – positive regulation of monocyte chemotaxis – response to heat – response to hypoxia – response to mechanical stimulus – response to peptide hormone stimulus – response to radiation

Chemokine (C-X-C Motif) Ligand 12 ist wie folgt lokalisiert:

extracellular region – extracellular space – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology