Die folgenden Gennamen und Gensymbole werden für Antigen Chemokine (C-C Motif) Receptor 2 über verschiedene Spezies hinweg verwendet:

chemokine (C-C motif) receptor 2 (Ccr2), chemokine (C-C motif) receptor 2 (CCR2)

Zu den weiteren Synonymen zählen:

Ckr2, Ccr2a, Ccr2b, Ckr2a, Ckr2b, mJe-r, Cmkbr2, Cc-ckr-2, CKR2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2, FLJ78302, MGC103828, MGC111760, MGC168006

Auf Proteinebene tauchen folgende Bezeichner für Antigen Chemokine (C-C Motif) Receptor 2 auf:

C-C chemokine receptor type 2 – CCR-2 – C-C CKR-2 – MIP-1 alphaR – MCP-1 receptor – JE/FIC receptor – chemokine (C-C) receptor 2 – chemoattractant protein-1 receptor – C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR) – chemokine (C-C motif) receptor 2 – OTTHUMP00000209947 – monocyte chemotactic protein 1 receptor – monocyte chemoattractant protein 1 receptor

Chemokine (C-C Motif) Receptor 2 erfüllt eine Reihe von Funktionen:

C-C chemokine binding – C-C chemokine receptor activity – G-protein coupled receptor activity – chemokine binding – cytokine binding – protein binding – protein homodimerization activity – receptor activity – signal transducer activity – CCR2 chemokine receptor binding

Chemokine (C-C Motif) Receptor 2 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – cellular calcium ion homeostasis – cellular defense response – chemokine-mediated signaling pathway – cytokine-mediated signaling pathway – hemopoiesis – humoral immune response – immune response – inflammatory response – negative regulation of angiogenesis – positive regulation of MAPKKK cascade – positive regulation of immune complex clearance by monocytes and macrophages – positive regulation of macrophage chemotaxis – regulation of cell migration – regulation of vascular endothelial growth factor production – sensory perception of pain – signal transduction – JAK-STAT cascade – chemotaxis – elevation of cytosolic calcium ion concentration – interspecies interaction between organisms – negative regulation of adenylate cyclase activity

Chemokine (C-C Motif) Receptor 2 ist wie folgt lokalisiert:

cytosol – dendrite – integral to membrane – membrane – neuronal cell body – perikaryon – perinuclear region of cytoplasm – plasma membrane – cytoplasm – integral to plasma membrane – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology